Evidence map›Paper›PMID 17710258›Full record

ReviewThe Analyst2007

Cellular impedance biosensors for drug screening and toxin detection.

Fareid Asphahani, Miqin Zhang

Abstract readReview
In one paragraph

Review in The Analyst, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 178 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. A review of bio-impedance devices.Medical & biological engineering & computing · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Fareid AsphahaniDepartment of Materials Science & Engineering, 302L Roberts Hall, University of Washington, Seattle, Washington 98195-2120, USA.
Miqin Zhang
University of Washington · US

Funding

Microelectrode arrays of single cell biosensorsR01GM075095 · NIGMS · UNIVERSITY OF WASHINGTON · PI ZHANG, MIQIN · 2006 to 2010
$1.3M
NIGMS NIH HHS R01 GM075095NIGMS NIH HHS R01GM075095
6 · The paper itself

Abstract

Cell-based impedance biosensing is an emerging technology that can be used to non-invasively and instantaneously detect and analyze cell responses to chemical and biological agents. This article highlights the fabrication and measurement technologies of cell impedance sensors, and their application in toxin detection and anti-cancer drug screening. We start with an introduction that describes the capability and advantages of cell-based sensors over conventional sensing technology, followed by a discussion of the influence of cell adhesion, spreading and viability during cell patterning on the subsequent impedance measurements and sensing applications. We then present an electronic circuit that models the cell-electrode system, by which the cellular changes can be detected in terms of impedance changes of the circuit. Finally, we discuss the current status on using cell impedance sensors for toxin detection and anti-cancer drug screening.

Indexed as

Biosensing TechniquesCell Physiological PhenomenaAntineoplastic AgentsCytotoxinsDrug Evaluation, PreclinicalElectric ImpedanceElectrochemistryHumansMicroarray AnalysisMicroelectrodesAntineoplastic AgentsCytotoxins

Identifiers

PMID17710258
PMCPMC3205117
OpenAlexW2053136465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.