ArticleNature chemical biology2007
Targeting the spliceosome.
Article in Nature chemical biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- The Role of Splicing Machinery as a Promising Potential Therapeutic Target for Pituitary Neuroendocrine Tumors (PitNETs).Cancers · 2026Review
- Spliceosome component TCERG1 regulates the aggressiveness of somatotroph adenoma.Journal of endocrinological investigation · 2025Article
- Insights into Mechanisms of Tumorigenesis in Neuroendocrine Neoplasms.International journal of molecular sciences · 2021Review
- Enantioselective Synthesis of a Cyclopropane Derivative of Spliceostatin A and Evaluation of Bioactivity.Organic letters · 2018Article
- Enantioselective Synthesis of Thailanstatin A Methyl Ester and Evaluation of in Vitro Splicing Inhibition.The Journal of organic chemistry · 2018Article
- Optimization of a Bioluminescence Resonance Energy Transfer-Based Assay for Screening of Trypanosoma cruzi Protein/Protein Interaction Inhibitors.Molecular biotechnology · 2018Article
- Enantioselective Synthesis of Spliceostatin G and Evaluation of Bioactivity of Spliceostatin G and Its Methyl Ester.Organic letters · 2018Article
- Evidence of nuclei-encoded spliceosome mediating splicing of mitochondrial RNA.Human molecular genetics · 2017Article
- Design, synthesis and in vitro splicing inhibition of desmethyl and carba-derivatives of herboxidiene.Organic & biomolecular chemistry · 2016Article
- Expression levels of SF3B3 correlate with prognosis and endocrine resistance in estrogen receptor-positive breast cancer.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2015Article
- Expanding rare disease drug trials based on shared molecular etiology.Nature biotechnology · 2014Article
- Article
- Re-evaluation of the role of calcium homeostasis endoplasmic reticulum protein (CHERP) in cellular calcium signaling.The Journal of biological chemistry · 2013Article
- Emerging roles of the spliceosomal machinery in myelodysplastic syndromes and other hematological disorders.Leukemia · 2012Review
- Expanding the range of 'druggable' targets with natural product-based libraries: an academic perspective.Current opinion in chemical biology · 2010Review
- Synthetic mRNA splicing modulator compounds with in vivo antitumor activity.Journal of medicinal chemistry · 2009Article
- Antitumor compounds based on a natural product consensus pharmacophore.Journal of medicinal chemistry · 2008Article
- The role of splicing factors in deregulation of alternative splicing during oncogenesis and tumor progression.Molecular & cellular oncologyReview
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
17710096What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.