ArticleInfection and immunity2007
Expression of Helicobacter pylori virulence factors and associated expression profiles of inflammatory genes in the human gastric mucosa.
Article in Infection and immunity, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 29 citations in OpenAlex.
- Co-expression network analysis and systems-level mapping of hub-bottleneck regulators deciphers the virulence architecture of Helicobacter pylori.Archives of microbiology · 2026Article
- Article
- MUC4 is a novel mediator inOncology letters · 2021Article
- Observational
- Combination of OipA, BabA, and SabA as candidate biomarkers for predicting Helicobacter pylori-related gastric cancer.Scientific reports · 2016Article
- Helicobacter pylori infection in patients with selective immunoglobulin a deficiency.Clinical and experimental immunology · 2016Article
- Influence of H. pylori CagA Coupled with Alcohol Consumption on Cytokine Profiles in Men.Medicine · 2016Observational
- Helicobacter pylori infection in patients with selective immunoglobulin E deficiency.World journal of gastroenterology · 2015Article
- Immunological detection of 34 KDa outer membrane protein as a functional form of OipA in clinical isolates of Helicobacter pylori.Iranian journal of microbiology · 2014Article
- Lower circulating levels of chemokine CXCL10 in Helicobacter pylori-infected patients with peptic ulcer: Influence of the bacterial virulence factor CagA.Iranian journal of microbiology · 2013Article
- Serum levels of high-sensitivity C-reactive protein (hs-CRP)in Helicobacter pylori-infected peptic ulcer patients and its association with bacterial CagA virulence factor.Digestive diseases and sciences · 2009Article
- Helicobacter pylori induces an antimicrobial response in rhesus macaques in a cag pathogenicity island-dependent manner.Gastroenterology · 2008Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helicobacter pylori virulence factors have been suggested to be important in determining the outcome of infection. The H. pylori adhesion protein BabA2 is thought to play a crucial role in bacterial colonization and in induction of severe gastric inflammation, particularly in combination with expression of CagA and VacA. However, the influence of these virulence factors on the pathogenesis of H. pylori infection is still poorly understood. To address this question, the inflammatory gene expression profiles for two groups of patients infected with triple-negative strains (lacking expression of cagA, babA2, and vacAs1 but expressing vacAs2) and triple-positive strains (expressing cagA, vacAs1, and babA2 but lacking expression of vacAs2) were investigated. The gene expression patterns in the antrum gastric mucosa from patients infected with different H. pylori strains were very similar, and no differentially expressed genes could be identified by pairwise comparisons. Our data thus suggest that there is a lack of correlation between the host inflammatory responses in the gastric mucosa and expression of the babA2, cagA, and vacAs1 genes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.