Evidence map›Paper›PMID 17706921›Full record

ReviewReproductive toxicology (Elmsford, N.Y.)

An evaluation of evidence for the carcinogenic activity of bisphenol A.

Ruth A Keri, Shuk-Mei Ho, Patricia A Hunt, Karen E Knudsen, Ana M Soto, Gail S Prins

Abstract readReview
In one paragraph

Review in Reproductive toxicology (Elmsford, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed.

  1. Review
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  12. Review
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  15. Environmental chemicals, breast cancer progression and drug resistance.Environmental health : a global access science source · 2020
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruth A KeriDepartment of Pharmacology and Division of General Medical Sciences--Oncology, Case Western Reserve University, Cleveland, OH 44160, USA.
Shuk-Mei Ho
Patricia A Hunt
Karen E Knudsen
Ana M Soto
Gail S Prins

Funding

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY RESEARCHP30ES006096 · NIEHS · UNIVERSITY OF CINCINNATI · PI YADAV, JAGJIT S · 1992 to 2022
$35.4M
Mechanisms of developmental toxicity of Bisphenol-AR01ES008314 · NIEHS · TUFTS UNIVERSITY BOSTON · PI SOTO, ANA · 1996 to 2016
$6.8M
Meiotic Studies of Chemicals With Estrogenic ActivityR01ES013527 · NIEHS · WASHINGTON STATE UNIVERSITY · PI HUNT, PATRICIA · 2005 to 2014
$4.5M
Epigenetic Basis for Prostate Carcinogenesis following Early Estrogenic ExposuresR01ES015584 · NIEHS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI HO, SHUK-MEI, PRINS, GAIL S · 2008 to 2012
$3.1M
Development Estrogenization of the Rat Prostate GlandR01DK040890 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PRINS, GAIL S · 1996 to 2010
$2.9M
Endocrine disruptors: AR regulation and prostate cancerR01ES016675 · NIEHS · UNIVERSITY OF CINCINNATI · PI KNUDSEN, KAREN E · 2007 to 2011
$1.9M
Bis-phenol A: Signaling and Mitogenesis in the ProstateR01CA093404 · NCI · UNIVERSITY OF CINCINNATI · PI KNUDSEN, KAREN E · 2002 to 2006
$1.2M
Development Modulation of Mouse Uterine TumorigenesisR21ES013071 · NIEHS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HO, SHUK-MEI · 2004 to 2006
$462k
Perinatal xenoestrogen exposure: epigenesis and neoplasiaR21ES015182 · NIEHS · TUFTS UNIVERSITY BOSTON · PI SOTO, ANA · 2006 to 2007
$462k
Prenatal xenoestrogen exposure and mammary cancerR21ES012301 · NIEHS · TUFTS UNIVERSITY BOSTON · PI SOTO, ANA · 2005 to 2006
$445k
Mammary cancer suceptibility following in utero exposure to bisphenol AR01ES015768 · NIEHS · CASE WESTERN RESERVE UNIVERSITY · PI KERI, RUTH A. · 2007 to 2008
$420k
Meiotic Studies of Chemicals with Estrogenic ActivityR56ES013527 · NIEHS · WASHINGTON STATE UNIVERSITY · PI GERONA, ROY ROBERTO R, HUNT, PATRICIA · 2017 to 2017
$250k
NCI NIH HHS CA93404NCI NIH HHS R01 CA093404NIDDK NIH HHS DK40890NIDDK NIH HHS R01 DK040890NIEHS NIH HHS ES012301NIEHS NIH HHS ES013071NIEHS NIH HHS ES013527NIEHS NIH HHS ES015182NIEHS NIH HHS ES015768NIEHS NIH HHS ES08314NIEHS NIH HHS ES12282NIEHS NIH HHS P30 ES006096NIEHS NIH HHS R01 ES008314NIEHS NIH HHS R01 ES013527NIEHS NIH HHS R01 ES015584NIEHS NIH HHS R01 ES015768NIEHS NIH HHS R01 ES016675NIEHS NIH HHS R21 ES012301NIEHS NIH HHS R21 ES013071NIEHS NIH HHS R21 ES015182NIEHS NIH HHS R56 ES013527
6 · The paper itself

Abstract

The National Institutes of Health (NIEHS, NIDCR) and the United States Environmental Protection Agency convened an expert panel of scientists with experience in the field of environmental endocrine disruptors, particularly with knowledge and research on bisphenol A (BPA). Five subpanels were charged to review the published literature and previous reports in five specific areas and to compile a consensus report with recommendations. These were presented and discussed at an open forum entitled "Bisphenol A: An Expert Panel Examination of the Relevance of Ecological, In Vitro and Laboratory Animal Studies for Assessing Risks to Human Health" in Chapel Hill, NC on 28-30 November 2006. The present review consists of the consensus report on the evidence for a role of BPA in carcinogenesis, examining the available evidence in humans and animal models with recommendations for future areas of research.

Indexed as

AnimalsBenzhydryl CompoundsBisphenol A CompoundsCarcinogensEndocrine DisruptorsHumansNational Institutes of Health (U.S.)PhenolsRisk AssessmentUnited StatesUnited States Environmental Protection AgencyBenzhydryl Compoundsbisphenol ABisphenol A CompoundsCarcinogensEndocrine DisruptorsPhenols

Identifiers

PMID17706921
PMCPMC2442886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.