Evidence map›Paper›PMID 17706914›Full record

ReviewGenomics2007

Comprehensive analysis of transport proteins encoded within the genome of Bdellovibrio bacteriovorus.

Ravi D Barabote, Snjezana Rendulic, Stephan C Schuster, Milton H Saier

Open access · greenAbstract readReview
In one paragraph

Review in Genomics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Biotechnological Potential ofFrontiers in microbiology · 2020
    Review
  9. Article
  10. Article
  11. Secretome of obligate intracellular Rickettsia.FEMS microbiology reviews · 2015
    Review
  12. Article
  13. Article
  14. Article
  15. Xenobiotic efflux in bacteria and fungi: a genomics update.Advances in enzymology and related areas of molecular biology · 2011
    Review
  16. Article
  17. Bioinformatic comparison of bacterial secretomes.Genomics, proteomics & bioinformatics · 2009
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ravi D BaraboteDivision of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA.
Snjezana Rendulic
Stephan C Schuster
Milton H Saier
Center for Disease Dynamics, Economics & Policy · USUniversity of California San Diego · US

Funding

The Transporter Classification Database (TCDB)R01GM077402 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SAIER, MILTON H. · 2006 to 2021
$4.7M
Mechanism of Carbohydrate Transport in BacteriaR01GM064368 · NIGMS · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI SAIER, MILTON H. · 2001 to 2004
$1.4M
ATP DEPENDENT PROTEIN KINASES IN GRAM POSITIVE BACTERIAR01GM055434 · NIGMS · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI SAIER, MILTON H. · 1997 to 2004
$1.1M
NIGMS NIH HHS GM 077402NIGMS NIH HHS GM 55434NIGMS NIH HHS GM 64368NIGMS NIH HHS R01 GM055434NIGMS NIH HHS R01 GM064368NIGMS NIH HHS R01 GM077402
6 · The paper itself

Abstract

Bdellovibrio bacteriovorus is a bacterial parasite with an unusual lifestyle. It grows and reproduces in the periplasm of a host prey bacterium. The complete genome sequence of B. bacteriovorus has recently been reported. We have reanalyzed the transport proteins encoded within the B. bacteriovorus genome according to the current content of the Transporter Classification Database. A comprehensive analysis is given on the types and numbers of transport systems that B. bacteriovorus has. In this regard, the potential protein secretory capabilities of at least four types of inner-membrane secretion systems and five types of outer-membrane secretion systems are described. Surprisingly, B. bacteriovorus has a disproportionate percentage of cytoplasmic membrane channels and outer-membrane porins. It has far more TonB/ExbBD-type systems and MotAB-type systems for energizing outer-membrane transport and motility than does Escherichia coli. Analysis of probable substrate specificities of its transporters provides clues to its metabolic preferences. Interesting examples of gene fusions and of potentially overlapping genes are also noted. Our analyses provide a comprehensive, detailed appreciation of the transport capabilities of B. bacteriovorus. They should serve as a guide for functional experimental analyses.

Indexed as

Genome, BacterialBdellovibrioCarrier ProteinsChromosome MappingCluster AnalysisSubstrate SpecificityTissue DistributionCarrier Proteins

Identifiers

PMID17706914
PMCPMC3415317
OpenAlexW2054770435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.