SynthesisSurgical endoscopy2008
Laparoscopic cholecystectomy for severe acute cholecystitis. A meta-analysis of results.
Synthesis in Surgical endoscopy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 62 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect Of Early Versus Delayed Laparoscopic Cholecystectomy On Postoperative Mortality, Morbidity and Difficult Cholecystectomy In Patients With Grade II Cholecystitis According To Tokyo 2018 Guidelines: Prospective Randomised Study
Characteristics of the Attention Provided to Patients With Cholecystitis in Villavicencio Hospitals, Colombia: A Retrospective Cross-sectional Trial.
A Real-world Study of Predictive Models of Gangrenous Cholecystitis Based on Machine Learning
Who cites it
62 citing papers in PubMed, 4 syntheses or guidelines pooled it, 170 citations in OpenAlex.
- Timing of early laparoscopic cholecystectomy for acute calculous cholecystitis: a meta-analysis of randomized clinical trials.World journal of emergency surgery : WJES · 2021Pooled it
- 2020 World Society of Emergency Surgery updated guidelines for the diagnosis and treatment of acute calculus cholecystitis.World journal of emergency surgery : WJES · 2020Guideline
- Prophylactic drainage after laparoscopic cholecystectomy for acute cholecystitis: a systematic review and meta-analysis.Updates in surgery · 2019Pooled it
- Intraoperative Variations of Cystic Artery and Duct in Laparoscopic Cholecystectomy: A Systematic Review With Meta-Analysis.ANZ journal of surgeryPooled it
- Preoperative prediction of acute severe cholecystitis using an attentive interpretable tabular network (TabNet)-based radiomics model and a stacking ensemble: a two-center study.Annals of medicine · 2026Article
- Cystic Duct Stenting Versus Other Treatment Modalities for the Management of Acute Cholecystitis in Patients with Decompensated Cirrhosis.Digestive diseases and sciences · 2025Article
- Development and validation of the ENDOLAP artificial intelligence framework for inflammation severity classification in laparoscopic cholecystectomy: a cross-sectional study.Surgical endoscopy · 2025Article
- An explainable predictive machine learning model of gangrenous cholecystitis based on clinical data: a retrospective single center study.World journal of emergency surgery : WJES · 2025Article
- Application of rules 1 to 6 for maximizing government infrastructure utilization in laparoscopic cholecystectomy: A case series analysis.Bioinformation · 2025Article
- The role of preoperative ultrasound in predicting conversion from laparoscopic cholecystectomy to open surgery in acute cholecystitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023Article
- Does the subtotal cholecystectomy rate for acute cholecystitis change with previous endoscopic retrograde cholangiopancreatography?Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023Article
- Surgical outcome of percutaneous transhepatic gallbladder drainage in acute cholecystitis: Ten years' experience at a tertiary care centre.Surgical endoscopy · 2022Article
- Laparoscopy in Emergency: Why Not? Advantages of Laparoscopy in Major Emergency: A Review.Life (Basel, Switzerland) · 2021Review
- Bile duct injuries (BDI) in the advanced laparoscopic cholecystectomy era.Surgical endoscopy · 2019Article
- Safe laparoscopic cholecystectomy: Adoption of universal culture of safety in cholecystectomy.World journal of gastrointestinal surgery · 2019Review
- Association of circulating inflammation proteins and gallstone disease.Journal of gastroenterology and hepatology · 2018Article
- Nondrainage after Laparoscopic Cholecystectomy for Acute Calculous Cholecystitis Does Not Increase the Postoperative Morbidity.BioMed research international · 2018Article
- Risk factors for difficulty of laparoscopic cholecystectomy in grade II acute cholecystitis according to the Tokyo guidelines 2013.BMC surgery · 2017Article
- Tokyo Guidelines 2013 may be too restrictive and patients with moderate and severe acute cholecystitis can be managed by early cholecystectomy too.Surgical endoscopy · 2017Article
- Optimal timing of cholecystectomy after percutaneous gallbladder drainage for severe cholecystitis.BMC gastroenterology · 2017Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this review was to evaluate surgical outcomes of laparoscopic cholecystectomy for gangrenous and empyematous acute cholecystitis defined as severe acute cholecystitis.
backgroundIt is not known to what extent surgical outcomes of laparoscopic cholecystectomy for severe acute cholecystitis differ from those for the nonsevere acute form, making it questionable whether urgent laparoscopic cholecystectomy is the best approach even in severe acute cases.
methodsLiterature searches were conducted to identify: (1) comparative studies which reported laparoscopic surgical outcomes separately for severe acute and nonsevere acute cholecystitis; (2) studies comparing such an approach with open cholecystectomy, subtotal laparoscopic cholecystectomy or cholecystostomy in severe acute cholecystitis. Results were pooled by standard meta-analytic techniques.
resultsSeven studies with a total of 1,408 patients undergoing laparoscopic cholecystectomy were found. The risks of conversion (RR 3.2, 95% CI 2.5 to 4.2) and overall postoperative complications (RR 1.6, 95% CI 1.2-2.2) were significantly higher in severe acute cholecystitis with respect to the nonsevere acute forms. However, no difference was detected as regards to local postoperative complications. No studies comparing open cholecystectomy or cholecystostomy with urgent laparoscopy were found.
conclusionA lower feasibility of laparoscopic cholecystectomy has been found for severe cholecystitis. A lower threshold of conversion is recommended since this may allow to reduce local postoperative complications. Literature data lack valuable comparative studies with other treatment modalities, which therefore need to be investigated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.