ArticleThe Journal of physiology1991
The medullary projections of afferent bronchopulmonary C fibres in the cat as shown by antidromic mapping.
Article in The Journal of physiology, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 70 citations in OpenAlex.
- Transformation of Our Understanding of Breathing Control by Molecular Tools.Annual review of physiology · 2023Review
- Analysis of the distribution of vagal afferent projections from different peripheral organs to the nucleus of the solitary tract in rats.The Journal of comparative neurology · 2022Article
- Molecular identity, anatomy, gene expression and function of neural crest vs. placode-derived nociceptors in the lower airways.Neuroscience letters · 2021Review
- Cough as an adverse effect on inhalation pharmaceutical products.British journal of pharmacology · 2020Review
- Peripheral-to-central immune communication at the area postrema glial-barrier following bleomycin-induced sterile lung injury in adult rats.Brain, behavior, and immunity · 2020Article
- Opposing effects of bronchopulmonary C-fiber subtypes on cough in guinea pigs.American journal of physiology. Regulatory, integrative and comparative physiology · 2018Article
- Role of the dorsomedial medulla in suppression of cough by codeine in cats.Respiratory physiology & neurobiology · 2017Article
- Microinjection of kynurenic acid in the rostral nucleus of the tractus solitarius disrupts spatiotemporal aspects of mechanically induced tracheobronchial cough.Journal of neurophysiology · 2017Article
- Dedicated C-fibre viscerosensory pathways to central nucleus of the amygdala.The Journal of physiology · 2017Article
- Article
- Peptide and lipid modulation of glutamatergic afferent synaptic transmission in the solitary tract nucleus.Frontiers in neuroscience · 2012Article
- Caudal nuclei of the rat nucleus of the solitary tract differentially innervate respiratory compartments within the ventrolateral medulla.Neuroscience · 2011Article
- An essential component to brainstem cough gating identified in anesthetized guinea pigs.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2010Article
- Central regulation of the cough reflex: therapeutic implications.Pulmonary pharmacology & therapeutics · 2009Review
- Cough sensors. I. Physiological and pharmacological properties of the afferent nerves regulating cough.Handbook of experimental pharmacology · 2009Review
- Sensory nerves and airway irritability.Handbook of experimental pharmacology · 2009Review
- Central pathways of pulmonary and lower airway vagal afferents.Journal of applied physiology (Bethesda, Md. : 1985) · 2006Review
- Lung C-fiber CNS reflex: role in the respiratory consequences of extended environmental tobacco smoke exposure in young guinea pigs.Environmental health perspectives · 2001Review
- Chronic passive cigarette smoke exposure augments bronchopulmonary C-fibre inputs to nucleus tractus solitarii neurones and reflex output in young guinea-pigs.The Journal of physiology · 2000Article
- Non-NMDA receptors transmit cardiopulmonary C fibre input in nucleus tractus solitarii in rats.The Journal of physiology · 1996Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
1. The activity of eighty-seven bronchopulmonary vagal afferent neurones with unmyelinated axons (C fibres) was recorded extracellularly in the nodose ganglia of decerebrate, paralysed and artificially ventilated cats. On the basis of their response latencies following the right atrial injection of capsaicin or phenyldiguanide, the cells were classified as having their receptor endings within the reach of pulmonary (latency less than 3.5 s) or bronchial (latency above 3.5 s) circulation. 2. Pulmonary and bronchial receptor cells differed only slightly in their response characteristics (firing rate, burst duration) and the conduction velocity of their peripheral axons. Bronchial C fibres represented about 70% of the population studied. 3. The medullary distributions of the central branches of six pulmonary and six bronchial C fibres were determined by means of the antidromic mapping technique. The two receptor subtypes did not differ in their central projection patterns. 4. Rostral to the obex, the central branches of the bronchopulmonary C fibres were localized within the medial portions of the nucleus tractus solitarii (NTS) and area postrema, and were most densely distributed along the borders of the parvicellular subnucleus of the NTS. Caudal to the obex, the most dense branching was found in the dorsal portion of the commissural subnucleus. Projections to the contralateral NTS were found, but these were of a much lower density. 5. The central distribution of bronchopulmonary C fibres is compared to the projection patterns of vagal and glossopharyngeal afferents of other modalities that are involved in respiratory and cardiovascular control. This is discussed in relation to the concept of a modality-specific organization of the NTS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.