ArticleThe EMBO journal2007
The TATA-binding protein regulates maternal mRNA degradation and differential zygotic transcription in zebrafish.
Article in The EMBO journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 65 citations in OpenAlex.
- Protein profiling of zebrafish embryos unmasks regulatory layers during early embryogenesis.Cell reports · 2024Article
- Quantitative proteomics reveals the dynamic proteome landscape of zebrafish embryos during the maternal-to-zygotic transition.iScience · 2024Article
- The miR-430 locus with extreme promoter density forms a transcription body during the minor wave of zygotic genome activation.Developmental cell · 2023Article
- Pluripotency factors determine gene expression repertoire at zygotic genome activation.Nature communications · 2022Article
- Article
- Zebrafish Models of Autosomal Dominant Ataxias.Cells · 2021Review
- Igf2bp3 maintains maternal RNA stability and ensures early embryo development in zebrafish.Communications biology · 2020Article
- Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing.Nature communications · 2020Article
- Single-molecule imaging correlates decreasing nuclear volume with increasing TF-chromatin associations during zebrafish development.Nature communications · 2018Article
- Histone variant H3.3-mediated chromatin remodeling is essential for paternal genome activation in mouse preimplantation embryos.The Journal of biological chemistry · 2018Article
- Transcriptome analysis of different developmental stages of amphioxus reveals dynamic changes of distinct classes of genes during development.Scientific reports · 2016Article
- DANIO-CODE: Toward an Encyclopedia of DNA Elements in Zebrafish.Zebrafish · 2016Article
- The Xenopus Maternal-to-Zygotic Transition from the Perspective of the Germline.Current topics in developmental biology · 2015Review
- The Maternal-to-Zygotic Transition During Vertebrate Development: A Model for Reprogramming.Current topics in developmental biology · 2015Review
- Diversity in TAF proteomics: consequences for cellular differentiation and migration.International journal of molecular sciences · 2014Review
- Global transcriptome analysis identifies regulated transcripts and pathways activated during oogenesis and early embryogenesis in Atlantic cod.Molecular reproduction and development · 2014Article
- Article
- Global regulation of mRNA translation and stability in the early Drosophila embryo by the Smaug RNA-binding protein.Genome biology · 2014Article
- The Atlantic Bonito (Sarda sarda, Bloch 1793) transcriptome and detection of differential expression during larvae development.PloS one · 2014Article
- Article
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Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early steps of embryo development are directed by maternal gene products and trace levels of zygotic gene activity in vertebrates. A major activation of zygotic transcription occurs together with degradation of maternal mRNAs during the midblastula transition in several vertebrate systems. How these processes are regulated in preparation for the onset of differentiation in the vertebrate embryo is mostly unknown. Here, we studied the function of TATA-binding protein (TBP) by knock down and DNA microarray analysis of gene expression in early embryo development. We show that a subset of polymerase II-transcribed genes with ontogenic stage-dependent regulation requires TBP for their zygotic activation. TBP is also required for limiting the activation of genes during development. We reveal that TBP plays an important role in the degradation of a specific subset of maternal mRNAs during late blastulation/early gastrulation, which involves targets of the miR-430 pathway. Hence, TBP acts as a specific regulator of the key processes underlying the transition from maternal to zygotic regulation of embryogenesis. These results implicate core promoter recognition as an additional level of differential gene regulation during development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.