Evidence map›Paper›PMID 17702556›Full record

ReviewCurrent opinion in immunology2007

Crosstalk at the initial encounter: interplay between host defense and ameba survival strategies.

Xiaoti Guo, Eric Houpt, William A Petri

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in immunology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xiaoti GuoDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA 22908-1340, USA.
Eric Houpt
William A Petri
University of Virginia · US

Funding

Cooperative Research Partnership for an Amebic Colitis VaccineU01AI070384 · NIAID · UNIVERSITY OF VIRGINIA · PI PETRI, WILLIAM A · 2006 to 2010
$4.1M
NIAID NIH HHS U01 AI070384
6 · The paper itself

Abstract

The host-parasite relationship is based on a series of interplays between host defense mechanisms and parasite survival strategies. Progress has been made in understanding the role of host immune response in amebiasis. While host cells elaborate diverse mechanisms for pathogen expulsion, amebae have also developed complex strategies to modulate host immune response and facilitate their own survival. This paper will give an overview of current research on the mutual interactions between host and Entamoeba histolytica in human and experimental amebiasis. Understanding this crosstalk is crucial for the effective design and implementation of new vaccines and drugs for this leading parasitic disease.

Indexed as

Host-Parasite InteractionsAnimalsAntibodies, ProtozoanEntamoeba histolyticaEntamoebiasisHumansImmunity, CellularImmunity, InnateImmunity, MucosalIntestinal MucosaAntibodies, Protozoan

Identifiers

PMID17702556
PMCPMC2679172
OpenAlexW2154115856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.