Evidence map›Paper›PMID 17702467›Full record

Trial reportFolia microbiologica2007

Treatment of orthopedic infections caused by resistant staphylococci.

D Jahoda, O Nyc, D Pokorný, I Landor, T Krůta, A Sosna

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Folia microbiologica, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

D Jahoda1st Orthopedic Clinic, 1st Medical Faculty, Charles University, 150 06 Prague, Czechia. david.jahoda@post.cz
O Nyc
D Pokorný
I Landor
T Krůta
A Sosna

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During 1999-2005 we treated 15 patients with linezolid for relevant infections of locomotion apparatus (7 cases with endoprosthesis infection, 5x osteomyelitis and 3x another infection). With the exception of one case the antibiotic therapy was always combined with appropriate surgical intervention. Average period of linezolid administration was 26 d; linezolid was applied from the beginning intravenously on average for 10 d, and then orally for 16 d (average). There were no undesirable effects in the file. Success rate reached 86.6%. MRSA strains were proved by standard methods: growth on Mueller-Hinton agar with increased concentration of NaCl and 2 mg/L of oxacilline, and measuring inhibitory zones around cephoxitine disk. The sensitivity to other antibiotics was specified by disk-diffusion test; that to linezolid was verified by E-test. Linezolid represents a medical reserve for the treatment of multiresistant Gram-positive infections or for emergencies, when allergy onset, high toxicity risk, intolerance, etc. do not allow to use other, in vitro effective, antibiotics.

Indexed as

AcetamidesAdultAgedAnti-Infective AgentsFemaleHumansLinezolidMaleMethicillin ResistanceMicrobial Sensitivity TestsMiddle AgedOsteomyelitisOxazolidinonesProsthesis-Related InfectionsStaphylococcal InfectionsStaphylococcus aureusAcetamidesAnti-Infective AgentsLinezolidOxazolidinones

Identifiers

PMID17702467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.