ArticleAmerican journal of human genetics2007
Recent genetic selection in the ancestral admixture of Puerto Ricans.
Article in American journal of human genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers.
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Who cites it
112 citing papers in PubMed.
- Genome-wide association analysis of circulating vitamin D levels in children with asthma.Human genetics · 2012Trial
- Evolutionary Signatures of Thermotolerance Shaped by Adaptive Admixtures in the Ghurrah Pig of India.Journal of molecular evolution · 2026Article
- Genomic insights into natural selection in recent human history.Nature reviews. Genetics · 2026Review
- Adaptive introgression shaping genomic adaptation and ancestral mosaicism of Changthangi sheep for high-altitude survival and pashmina excellence.BMC genomics · 2026Article
- Genome-wide SNP evidence for the genetic uniqueness of indigenous cattle population.Mammalian genome : official journal of the International Mammalian Genome Society · 2025Article
- Article
- Genome wide locus-specific ancestry analysis revealed adaptive admixtures in crossbred cattle of India.Scientific reports · 2025Article
- Ancient dog introgression into the Iberian wolf genome may have facilitated adaptation to human-dominated landscapes.Genome research · 2025Article
- Old vs. New Local Ancestry Inference in HCHS/SOL: A Comparative Study.bioRxiv : the preprint server for biology · 2025Article
- Characterizing substructure via mixture modeling in large-scale genetic summary statistics.American journal of human genetics · 2025Article
- Social determinants of participation in genetic research among Puerto Ricans and in the Puerto Rican diaspora.Social science & medicine (1982) · 2024Article
- Characterizing substructure via mixture modeling in large-scale genetic summary statistics.bioRxiv : the preprint server for biology · 2024Article
- The temporal and genomic scale of selection following hybridization.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genetic ancestry is related to potential sources of breast cancer health disparities among Colombian women.PloS one · 2024Article
- Global and Local Ancestry and its Importance: A Review.Current genomics · 2024Review
- Joint multi-ancestry and admixed GWAS reveals the complex genetics behind human cranial vault shape.Nature communications · 2023Review
- Inferring multi-locus selection in admixed populations.PLoS genetics · 2023Article
- The temporal and genomic scale of selection following hybridization.bioRxiv : the preprint server for biology · 2023Article
- Localizing Post-Admixture Adaptive Variants with Object Detection on Ancestry-Painted Chromosomes.Molecular biology and evolution · 2023Article
- Fast, accurate local ancestry inference with FLARE.American journal of human genetics · 2023Article
52 more citing papers are in PubMed but not listed here.
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7 authors.
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Abstract
Recent studies have used dense markers to examine the human genome in ancestrally homogeneous populations for hallmarks of selection. No genomewide studies have focused on recently admixed groups--populations that have experienced admixing among continentally divided ancestral populations within the past 200-500 years. New World admixed populations are unique in that they represent the sudden confluence of geographically diverged genomes with novel environmental challenges. Here, we present a novel approach for studying selection by examining the genomewide distribution of ancestry in the genetically admixed Puerto Ricans. We find strong statistical evidence of recent selection in three chromosomal regions, including the human leukocyte antigen region on chromosome 6p, chromosome 8q, and chromosome 11q. Two of these regions harbor genes for olfactory receptors. Interestingly, all three regions exhibit deficiencies in the European-ancestry proportion.
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