Evidence map›Paper›PMID 17697886›Full record

ReviewMethods in enzymology2007

Studies on integrins in the nervous system.

Sumiko Denda, Louis F Reichardt

Open access · greenAbstract readReview
In one paragraph

Review in Methods in enzymology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Overview: studying integrins in vivo.Methods in molecular biology (Clifton, N.J.) · 2012
    Review
  9. Article
  10. The emerging role of integrins in neuropsychiatric disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2010
    Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sumiko DendaShiseido Research Center 2, Kanazawa-ku, Yokohama, Japan.
Louis F Reichardt
University of California, San Francisco · US

Funding

STUDIES ON A NEURTITE OUTGROWTH FACTORR01NS019090 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI REICHARDT, LOUIS FRENCH · 1985 to 2009
$3.4M
NINDS NIH HHS R01 NS019090
6 · The paper itself

Abstract

Integrins are of interest to neuroscientists because they and many of their ligands are widely expressed in the nervous system and have been shown to have diverse roles in neural development and function (Clegg et al., 2003; Li and Pleasure, 2005; Pinkstaff et al., 1998, 1999; Reichardt and Tomaselli, 1991; Schmid et al., 2005). Integrins have also been implicated in control of pathogenesis in several neurodegenerative diseases, brain tumor pathogenesis, and the aftermath of brain and peripheral nervous system injury (Condic, 2001; Ekstrom et al., 2003; Kloss et al., 1999; Verdier and Penke, 2004; Wallquist et al., 2004). Using integrin antagonists as therapeutic agents in a variety of neurological diseases is of great interest at present (Blackmore and Letourneau, 2006; Mattern et al., 2005; Polman et al., 2006; Wang et al., 2006). In this chapter, we describe methods used in our laboratory to characterize neuronal responses to extracellular matrix proteins, and procedures for assessing integrin roles in neuronal cell attachment and differentiation.

Indexed as

Nervous System Physiological PhenomenaAnimalsCell Culture TechniquesCells, CulturedIntegrinsNervous SystemNeuronsIntegrins

Identifiers

PMID17697886
PMCPMC2623243
OpenAlexW1538191307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.