Evidence map›Paper›PMID 17697637›Full record

ArticleCurrent allergy and asthma reports2007

Hereditary immunologic disorders caused by pyrin and cryopyrin.

Hal M Hoffman

Abstract read
PubMed Publisher
In one paragraph

Article in Current allergy and asthma reports, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Inflammasomes as polyvalent cell death platforms.Cellular and molecular life sciences : CMLS · 2016
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Hal M HoffmanDivision of Rheumatology, Allergy, and Immunology, University of California at San Diego Medical School, 9500 Gilman Drive, La Jolla, CA 92093-0635, USA. hahoffman@ucsd.edu
University of California San Diego Medical Center · US

Funding

The Role of Cryopyrin in Autoinflammatory DiseasesR01AI052430 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HOFFMAN, HAROLD M · 2002 to 2011
$3.4M
NIAID NIH HHS R01-AI052430
6 · The paper itself

Abstract

A new family of hereditary immunologic disorders known as the autoinflammatory diseases involves dysregulation of the innate immune system. Elucidation of the genetic basis of these disorders has resulted in improved understanding of the disease pathophysiology of systemic and tissue inflammation, and has also revealed novel nonpathologic innate immune mechanisms. These advances have also resulted in direct improvement in diagnosis and therapy for autoinflammatory disorders such as the cryopyrinopathies and familial Mediterranean fever and have implications for more common inflammatory diseases.

Indexed as

Autoimmune DiseasesCarrier ProteinsCytoskeletal ProteinsFamilial Mediterranean FeverHumansNLR Family, Pyrin Domain-Containing 3 ProteinPyrinCarrier ProteinsCytoskeletal ProteinsMEFV protein, humanNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanPyrin

Identifiers

PMID17697637
OpenAlexW2076904021

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.