ArticleCroatian medical journal2007
Y-chromosome short tandem repeat DYS458.2 non-consensus alleles occur independently in both binary haplogroups J1-M267 and R1b3-M405.
Article in Croatian medical journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Exploring the Y Chromosomal Ancestry of Modern Panamanians.PloS one · 2015Trial
- A comprehensive analysis of Y-chromosomal diversity in Colombian populations.International journal of legal medicine · 2026Article
- The Qatari population's genetic structure and gene flow as revealed by the Y chromosome.PloS one · 2023Article
- Comparative Y-chromosome analysis among Cypriots in the context of historical events and migrations.PloS one · 2021Article
- Middle eastern genetic legacy in the paternal and maternal gene pools of Chuetas.Scientific reports · 2020Article
- Development of the Kazakhstan Y-chromosome haplotype reference database: analysis of 27 Y-STR in Kazakh population.International journal of legal medicine · 2019Article
- A phylogenetic framework facilitates Y-STR variant discovery and classification via massively parallel sequencing.Forensic science international. Genetics · 2018Article
- The Y chromosome as the most popular marker in genetic genealogy benefits interdisciplinary research.Human genetics · 2017Review
- Novel Y-chromosome Short Tandem Repeat Variants Detected Through the Use of Massively Parallel Sequencing.Genomics, proteomics & bioinformatics · 2015Article
- Paleo-Balkan and Slavic contributions to the genetic pool of Moldavians: insights from the Y chromosome.PloS one · 2013Article
- Article
- Understanding the Y chromosome variation in Korea--relevance of combined haplogroup and haplotype analyses.International journal of legal medicine · 2012Article
- Article
- Haplotype frequencies of 17 Y-chromosomal short tandem repeat loci from the Cukurova region of Turkey.Croatian medical journal · 2011Article
- A major Y-chromosome haplogroup R1b Holocene era founder effect in Central and Western Europe.European journal of human genetics : EJHG · 2011Article
- Population genetic analysis of haplotypes based on 17 short tandem repeat loci on Y chromosome in population sample from eastern Croatia.Croatian medical journal · 2010Article
- Moors and Saracens in Europe: estimating the medieval North African male legacy in southern Europe.European journal of human genetics : EJHG · 2009Article
- Y-chromosome short tandem repeat intermediate variant alleles DYS392.2, DYS449.2, and DYS385.2 delineate new phylogenetic substructure in human Y-chromosome haplogroup tree.Croatian medical journal · 2009Article
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
aimTo determine the human Y-chromosome haplogroup backgrounds of non-consensus DYS458.2 short tandem repeat alleles and evaluate their phylogenetic substructure and frequency in representative samples from the Middle East, Europe, and Pakistan.
methodsMolecular characterization of lineages was achieved using a combination of Y-chromosome haplogroup defining binary polymorphisms and up to 37 short tandem repeat loci, including DYS388 to construct haplotypes. DNA sequencing of the DYS458 locus and median-joining network analyses were used to evaluate Y-chromosome lineages displaying the DYS458.2 motif.
resultsWe showed that the DYS458.2 allelic innovation arose independently on at least two distinctive binary haplogroup backgrounds and possibly a third as well. The partial allele length pattern was fixed in all haplogroup J1 chromosomes examined, including its known rare sub-haplogroups. Within the alternative R1b3 associated M405 defined sub-haplogroup, both DYS458.0 and DYS458.2 allele classes occurred. A single chromosome also allocated to the R1b3-M269*(xM405) classification. The physical position of the partial insertion/deletion occurrence within the normal tetramer tract differed distinctly in each haplogroup context.
conclusionsWhile unusual DYS458.2 alleles are informative, additional information for other linked polymorphic loci is required when using such non-conforming alleles to infer haplogroup background and common ancestry.
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