ReviewImmunologic research2007
Human gamma delta T cells: candidates for the development of immunotherapeutic strategies.
Review in Immunologic research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Article
- T Cell Peptide Prediction, Immune Response, and Host-Pathogen Relationship in Vaccinated and Recovered from Mild COVID-19 Subjects.Biomolecules · 2024Article
- Association of KIR Genes with Middle East Respiratory Syndrome Coronavirus Infection in South Koreans.Journal of clinical medicine · 2024Article
- Review
- Human immunology and immunotherapy: main achievements and challenges.Cellular & molecular immunology · 2021Review
- Distinct CD4Frontiers in immunology · 2021Article
- Bispecific Antibody PD-L1 x CD3 Boosts the Anti-Tumor Potency of the Expanded Vγ2Vδ2 T Cells.Frontiers in immunology · 2021Article
- Optimized protocols for γδ T cell expansion and lentiviral transduction.Molecular medicine reports · 2019Article
- A Subset of Protective γ9δ2 T Cells Is Activated by Novel Mycobacterial Glycolipid Components.Infection and immunity · 2016Article
- Study of the biological features ofBiomedical reports · 2016Article
- Activation status of γδ T cells dictates their effect on osteoclast generation and bone resorption.Bone reports · 2015Article
- Empowering gamma delta T cells with antitumor immunity by dendritic cell-based immunotherapy.Oncoimmunology · 2015Review
- The safety of allogeneic innate lymphocyte therapy for glioma patients with prior cranial irradiation.Cancer immunology, immunotherapy : CII · 2015Article
- Zoledronic acid causes γδ T cells to target monocytes and down-modulate inflammatory homing.Immunology · 2014Article
- The co-stimulatory effects of MyD88-dependent Toll-like receptor signaling on activation of murine γδ T cells.PloS one · 2014Article
- Review
- Defining the nature of human γδ T cells: a biographical sketch of the highly empathetic.Cellular & molecular immunology · 2013Review
- Granzyme A produced by γ(9)δ(2) T cells induces human macrophages to inhibit growth of an intracellular pathogen.PLoS pathogens · 2013Article
- Review
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A numerically small subset of human T lymphocytes expresses a gamma delta T cell receptor (TCR). These gamma delta T cells share certain effector functions with alpha beta T cells as well as with NK cells and NKT cells. The major peripheral blood gamma delta T cell subset in healthy adults expresses a Vgamma9Vdelta2 TCR, which recognizes small phosphorylated metabolites referred to as phosphoantigens. Vdelta1 gamma delta T cells mainly occur in the intestine. They recognize the stress-induced MICA/B and CD1c. Furthermore, gamma delta T cells express a variety of NK cell and pattern-recognition receptors which are responsible for the "fine-tuning" of effector functions. In recent years, gamma delta T cells start to emerge as a rewarding target for immunotherapeutic strategies against viral infections and cancer. A better understanding of factors that modulate gamma gamma delta T cell function will further eluminate the potential of these cells.
Indexed as
Identifiers
17695246What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.