Evidence map›Paper›PMID 17690854›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2007

Variable responses to rituximab treatment in neuromyelitis optica (Devic's disease).

M Capobianco, S Malucchi, A di Sapio, F Gilli, A Sala, R Bottero, F Marnetto, C Doriguzzi Bozzo, A Bertolotto

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Review
  3. Observational
  4. Article
  5. Efficacy and safety of rituximab in neuromyelitis optica: Review of evidence.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017
    Review
  6. Review
  7. Article
  8. Observational
  9. Article
  10. Review
  11. Review
  12. Current options for the treatment of optic neuritis.Clinical ophthalmology (Auckland, N.Z.) · 2012
    Article
  13. Review
  14. Review
  15. Article
  16. Current and future treatment approaches for neuromyelitis optica.Therapeutic advances in neurological disorders · 2011
    Article
  17. Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica.Proceedings of the National Academy of Sciences of the United States of America · 2011
    Article
  18. Article
  19. Neuromyelitis optica: diagnosis, pathogenesis, and treatment.Current neurology and neuroscience reports · 2008
    Review
  20. Immune agents for the treatment of Devic's neuromyelitis optica.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2007
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

M CapobiancoCentro di Riferimento Regionale Sclerosi Multipla & Neurobiologia Clinica - ASO S. Luigi Gonzaga, Regione Gonzole 10, I-10043, Orbassano (TO), Italy. sclerosi.multipla@sanluigi.piemonte.it
S Malucchi
A di Sapio
F Gilli
A Sala
R Bottero
F Marnetto
C Doriguzzi Bozzo
A Bertolotto

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have described two cases of Devic's disease patients treated with rituximab with different outcomes. The results indicate that there may be early unresponsiveness in very aggressive cases. Well designed clinical trials are needed to assess treatment effects in such a rare disease.

Indexed as

AdultAntibodies, MonoclonalAntibodies, Monoclonal, Murine-DerivedBrainFemaleHumansImmunologic FactorsMagnetic Resonance ImagingNeuromyelitis OpticaRituximabSpinal CordAntibodies, MonoclonalAntibodies, Monoclonal, Murine-DerivedImmunologic FactorsRituximab

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.