ArticleThe EMBO journal2007
LysM domains mediate lipochitin-oligosaccharide recognition and Nfr genes extend the symbiotic host range.
Article in The EMBO journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 153 papers.
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Who cites it
153 citing papers in PubMed.
- Coordination of PTI and ETI in legume-rhizobium mutualism.aBIOTECH · 2026Review
- Cyclophilin A-mediated cis/trans isomerization modulates RIN4 to control intracellular rhizobial infection in legumes.The New phytologist · 2026Article
- Plant cell surface receptors.The Plant journal : for cell and molecular biology · 2026Review
- Shedding light on receptor kinase processing.PLoS pathogens · 2025Article
- Cysteine-rich receptor-like secreted protein 1 promotes intercellular infection and enhances nodulation inHorticulture research · 2025Article
- Article
- Enacting partner specificity in legume-rhizobia symbioses.aBIOTECH · 2025Review
- Ethylene promotes SMAX1 accumulation to inhibit arbuscular mycorrhiza symbiosis.Nature communications · 2025Article
- The Type III Effector NopM from Bradyrhizobium elkanii USDA61 Induces a Hypersensitive Response in Lotus japonicus Root Nodules.Microbes and environments · 2025Article
- A conserved juxtamembrane motif in plant NFR5 receptors is essential for root nodule symbiosis.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Species-specific microsymbiont discrimination mediated by aScience advances · 2024Article
- Comparative genomic and transcriptomic analyses provide new insight into symbiotic host specificity.iScience · 2024Article
- Nitrogen and Nod factor signaling determine Lotus japonicus root exudate composition and bacterial assembly.Nature communications · 2024Article
- Signaling in Legume-Rhizobia Symbiosis.International journal of molecular sciences · 2023Review
- Single-cell analysis identifies genes facilitating rhizobium infection in Lotus japonicus.Nature communications · 2023Article
- A complex regulatory network governs the expression of symbiotic genes inFrontiers in plant science · 2023Article
- Exploring the role of plant lysin motif receptor-like kinases in regulating plant-microbe interactions in the bioenergy cropComputational and structural biotechnology journal · 2023Article
- PairedProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Nod factor perception: an integrative view of molecular communication during legume symbiosis.Plant molecular biology · 2022Review
- Constitutive overexpression of GsIMaT2 gene from wild soybean enhances rhizobia interaction and increase nodulation in soybean (Glycine max).BMC plant biology · 2022Article
93 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Legume-Rhizobium symbiosis is an example of selective cell recognition controlled by host/non-host determinants. Individual bacterial strains have a distinct host range enabling nodulation of a limited set of legume species and vice versa. We show here that expression of Lotus japonicus Nfr1 and Nfr5 Nod-factor receptor genes in Medicago truncatula and L. filicaulis, extends their host range to include bacterial strains, Mesorhizobium loti or DZL, normally infecting L. japonicus. As a result, the symbiotic program is induced, nodules develop and infection threads are formed. Using L. japonicus mutants and domain swaps between L. japonicus and L. filicaulis NFR1 and NFR5, we further demonstrate that LysM domains of the NFR1 and NFR5 receptors mediate perception of the bacterial Nod-factor signal and that recognition depends on the structure of the lipochitin-oligosaccharide Nod-factor. We show that a single amino-acid variation in the LysM2 domain of NFR5 changes recognition of the Nod-factor synthesized by the DZL strain and suggests a possible binding site for bacterial lipochitin-oligosaccharide signal molecules.
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