Trial reportAnnals of epidemiology2007
The impact of HIPAA authorization on willingness to participate in clinical research.
Trial report in Annals of epidemiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 28 citations in OpenAlex.
- Health Insurance Portability and Accountability Act (HIPAA) authorization and survey nonresponse bias.Medical care · 2011Trial
- Barriers to and solutions for representative inclusion across the lifespan and in life course research: The need for structural competency highlighted by the COVID-19 pandemic.Journal of clinical and translational science · 2023Review
- The difficulties of broad data sharing in genomic medicine: Empirical evidence from diverse participants in prenatal and pediatric clinical genomics research.Genetics in medicine : official journal of the American College of Medical Genetics · 2022Article
- Perceived protectiveness of research safeguards and influences on willingness to participate in research: A novel MTurk pilot study.Journal of psychiatric research · 2021Article
- Privacy and confidentiality in pragmatic clinical trials.Clinical trials (London, England) · 2015Article
- An opportunity for cancer prevention during preadolescence and adolescence: stopping human papillomavirus (HPV)-related cancer through HPV vaccination.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2013Article
- Large-scale evaluation of automated clinical note de-identification and its impact on information extraction.Journal of the American Medical Informatics Association : JAMIA · 2013Article
- Preconsent education about research processes improved African Americans' willingness to participate in clinical research.Journal of clinical epidemiology · 2011Article
- Challenges to Engaging Black Male Victims of Community Violence in Healthcare Research: Lessons Learned From Two Studies.Psychological trauma : theory, research, practice and policy · 2010Article
- Going the distance: overcoming challenges in recruitment and retention of Black and White women in multisite, longitudinal study of predictors of coronary heart disease.Research in gerontological nursing · 2009Article
- Research participation by older adults at end of life: barriers and solutions.Research in gerontological nursing · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeThis study systematically examined the impact of inclusion of Health Insurance Portability and Accountability Act (HIPAA) authorization on the willingness of African Americans of diverse sociodemographic characteristics to participate in a clinical research study and explored reasons for nonparticipation.
methodsFor a purposive sample of 384 African American outpatients at four metropolitan primary care clinics from August 2005 through May 2006, willingness to participate in a hypothetic clinical research study of an antihypertensive medication under one of two experimental conditions was compared. Interviewees were randomly assigned to undergo informed consent alone (control group) or informed consent with HIPAA authorization (HIPAA group). They were asked whether they would participate and reasons for their decisions.
resultsA smaller proportion of interviewees in the HIPAA group were willing to enroll in the study (27% vs. 39%; p = 0.02), with an adjusted odds ratio of 0.56 (95% confidence interval = 0.36-0.91). Those in the HIPAA group were more likely to give reasons related to privacy (p < 0.001), poor understanding of the form (p = 0.01), and mistrust or fear of research (p = 0.04) for nonparticipation.
conclusionsThe inclusion of HIPAA authorization within the informed consent process may adversely affect the willingness of African Americans to participate in clinical research and may raise concerns about privacy, understanding the forms, and mistrust or fear of research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.