ReviewCurrent opinion in biotechnology2007
Logic of gene regulatory networks.
Review in Current opinion in biotechnology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- MICA: a multi-omics method to predict gene regulatory networks in early human embryos.Life science alliance · 2024Article
- Single-cell transcriptomic signatures and gene regulatory networks modulated by Wls in mammalian midline facial formation and clefts.Development (Cambridge, England) · 2022Article
- Roadmap for the multiscale coupling of biochemical and mechanical signals during development.Physical biology · 2021Review
- Importance of Long Non-coding RNAs in the Development and Disease of Skeletal Muscle and Cardiovascular Lineages.Frontiers in cell and developmental biology · 2019Review
- Design specifications for cellular regulation.Theory in biosciences = Theorie in den Biowissenschaften · 2016Article
- Eric Davidson: Steps to a gene regulatory network for development.Developmental biology · 2016Article
- Structure of developmental gene regulatory networks from the perspective of cell fate-determining genes.Transcription · 2016Review
- Extended evolution: A conceptual framework for integrating regulatory networks and niche construction.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2015Article
- Protein networks as logic functions in development and cancer.PLoS computational biology · 2011Article
- A synthetic genetic edge detection program.Cell · 2009Article
- Gene expression and regulation of higher plants under soil water stress.Current genomics · 2009Article
- Geometric control of tissue morphogenesis.Biochimica et biophysica acta · 2009Review
- The sea urchin genome as a window on function.The Biological bulletin · 2008Article
- The Comet Cometh: Evolving Developmental Systems.Biological theoryArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Regulatory networks of transcription factors and signaling molecules lie at the heart of development. Their architecture implements logic functions whose execution propels cells from one regulatory state to the next, thus driving development forward. As an example of a subcircuit that translates transcriptional input into developmental output, we consider a particularly simple case, the regulatory processes underlying pigment cell formation in sea urchin embryos. The regulatory events in this process can be represented as elementary logic functions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.