ArticleBreast cancer research : BCR2007
Mammary stem cell number as a determinate of breast cancer risk.
Article in Breast cancer research : BCR, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
42 citing papers in PubMed.
- Birthweight, height, and body mass index in relation to the expression of stem cell markers among women with benign breast biopsies in the Nurses' Health Study II.British journal of cancer · 2025Article
- Associations of Stem Cell Markers with Lobular Involution in Benign Breast Tissue.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Associations of circulating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 with the expression of stem cell markers in benign breast tissue.Breast cancer research : BCR · 2025Article
- Associations of Early-Life and Adult Anthropometric Measures with the Expression of Stem Cell Markers CD44, CD24, and ALDH1A1 in Women with Benign Breast Biopsies.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Article
- Understanding the mechanisms underlying obesity in remodeling the breast tumor immune microenvironment: from the perspective of inflammation.Cancer biology & medicine · 2023Review
- The Role of Cow's Milk Consumption in Breast Cancer Initiation and Progression.Current nutrition reports · 2023Review
- Associations of stem cell markers in benign breast tissue with subsequent breast cancer risk.American journal of cancer research · 2023Article
- Obesity reduces mammary epithelial cell TGFβ1 activity through macrophage-mediated extracellular matrix remodeling.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020Article
- Associations of mammographic breast density with breast stem cell marker-defined breast cancer subtypes.Cancer causes & control : CCC · 2019Article
- Dietary polyunsaturated fatty acids modulate adipose secretome and is associated with changes in mammary epithelial stem cell self-renewal.The Journal of nutritional biochemistry · 2019Article
- The association between weight at birth and breast cancer risk revisited using Mendelian randomisation.European journal of epidemiology · 2019Article
- Plasticity and Potency of Mammary Stem Cell Subsets During Mammary Gland Development.International journal of molecular sciences · 2019Review
- Mathematical modeling reveals the factors involved in the phenomena of cancer stem cells stabilization.PloS one · 2019Article
- Vitamin D-induced vitamin D receptor expression induces tamoxifen sensitivity in MCF-7 stem cells via suppression of Wnt/β-catenin signaling.Bioscience reports · 2018Article
- Cadmium Exposure Inhibits Branching Morphogenesis and Causes Alterations Consistent With HIF-1α Inhibition in Human Primary Breast Organoids.Toxicological sciences : an official journal of the Society of Toxicology · 2018Article
- Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.Breast cancer research : BCR · 2017Article
- Tissue-based associations of mammographic breast density with breast stem cell markers.Breast cancer research : BCR · 2017Article
- Prognostic impact of CD133 expression in Endometrial Cancer Patients.Scientific reports · 2017Article
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No grant is acknowledged in the PubMed record.
Abstract
The 'cancer stem cell hypothesis' posits that cancers, including breast cancer, arise in tissue stem or progenitor cells. If this is the case, then it follows that the risk for developing breast cancer may be determined in part by the number of breast stem/progenitor cells that can serve as targets for transformation. Stem cell number may be set during critical windows of development, including in utero, adolescence, and pregnancy. The growth hormone/insulin-like growth factor-1 axis may play an important role in regulating breast stem cell number during these developmental windows, suggesting an important link between this signaling pathway and breast cancer risk.
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