ReviewVeterinary journal (London, England : 1997)2008
The feline acute phase reaction.
Review in Veterinary journal (London, England : 1997), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
64 citing papers in PubMed, 128 citations in OpenAlex.
- Clinical applications of blood cell ratios in veterinary hematology: From diagnosis to prognosis.Veterinary and animal science · 2026Review
- Acute Phase Proteins in Cats Naturally Infected or Seropositive forAnimals : an open access journal from MDPI · 2026Article
- The comparison of acute phase proteins in experimentally induced canine acute pancreatitis.BMC veterinary research · 2026Article
- Association of inflammation with glycemic control, insulin sensitivity, and beta-cell function in diabetic cats.Journal of veterinary internal medicine · 2026Article
- Effect of trauma on the concentration of selected feline acute phase proteins.Journal of feline medicine and surgery · 2026Article
- Evaluation of amyloid A and haptoglobin in the serum of cats with respiratory diseases.Frontiers in veterinary science · 2026Article
- Serum Amyloid A and Haptoglobin as Markers in Cats with Gingivitis-Preliminary Study.Veterinary medicine and science · 2025Article
- Evaluation of selected inflammatory markers in cats with feline infectious peritonitis before and after therapy.BMC veterinary research · 2025Article
- Investigation of the Correlation Between ELISA and Serum Amyloid A in the Diagnosis of Bordetella bronchiseptica in Dogs.Veterinary medicine and science · 2025Article
- Comparative Analysis of Acute-Phase Protein Profiles in Cats Undergoing Ovariectomy: Laparoscopic vs. Conventional Surgery in Short Time After Procedure.Animals : an open access journal from MDPI · 2024Article
- Postoperative monitoring of ovariohysterectomy carried out with two types of surgical sutures in shelter cats and differences in selected blood parameters between shelter and pet cats.BMC veterinary research · 2024Article
- The Diagnostic Value of Serum Amyloid A and Other Laboratory and Clinical Variables in Cats with Increased Liver Enzyme Activity.Veterinary sciences · 2024Article
- Moderate to advanced periodontitis contributes to increased oxidative stress in cats: a case-control study.BMC veterinary research · 2024Article
- Inflammatory Status and Chronic Kidney Disease in Cats: Old and New Inflammatory Markers-A Pilot Prospective Study.Animals : an open access journal from MDPI · 2023Article
- Evaluation of blood serum iron concentration as an alternative biomarker for inflammation in dairy cows.Biological trace element research · 2023Article
- Acute phase proteins and total antioxidant capacity in free-roaming cats infected by pathogenic leptospires.BMC veterinary research · 2023Article
- A Retrospective Comparative Evaluation of Selected Blood Cell Ratios, Acute Phase Proteins, and Leukocyte Changes Suggestive of Inflammation in Cats.Animals : an open access journal from MDPI · 2023Article
- Serum amyloid A in cats with renal azotemia.Veterinary world · 2023Article
- Simplified Light's Criteria and Acute Phase Proteins Reflect Aetiology of Feline Body Cavity Effusions Better than the Traditional Classification Scheme.Animals : an open access journal from MDPI · 2023Article
- Circulating oxidative stress and acute phase protein levels in horses infested with ticks.Experimental & applied acarology · 2023Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The acute phase reaction (APR) is a response to potentially pathogenic stimuli. It begins with the release of interleukin (IL)-1, IL-6 and tumour necrosis factor (TNF)-alpha from inflammatory cells. These cytokines induce fever, leucocytosis and release of serum acute phase proteins (APPs). In this review, the characteristics of the feline APR are described. In cats with inflammatory conditions, fever is a common finding, with leucocytosis due to the release of cells from the marginal pool, followed by activation of myelopoiesis. Because excitement frequently causes leucocytosis in cats, a diagnosis of inflammation should therefore be supported by additional findings such as the presence of toxic neutrophils. The major APPs are serum amyloid A and alpha(1)-acid glycoprotein (AGP), which both increase a few hours after the inflammatory stimulus and remain elevated for as long as the inflammation persists. AGP plays an important role in the diagnosis of feline infectious peritonitis (FIP) and may also be useful also in studies of FIP pathogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.