ArticleBiological psychology2007
Nociceptive flexion reflex thresholds and pain during rest and computer game play in patients with hypertension and individuals at risk for hypertension.
Article in Biological psychology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 27 citations in OpenAlex.
- Stress and pain: modality-specific opioid mediation of stress-induced analgesia.Journal of neural transmission (Vienna, Austria : 1996) · 2021Trial
- Effects of opioid blockade on nociceptive flexion reflex thresholds and nociceptive responding in hypertensive and normotensive individuals.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2008Trial
- Effects of naltrexone on electrocutaneous pain in patients with hypertension compared to normotensive individuals.Biological psychology · 2008Trial
- Article
- Anger Inhibition and Pain Modulation.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2019Article
- Stress and Addiction: When a Robust Stress Response Indicates Resiliency.Psychosomatic medicine · 2018Review
- Emotional Modulation of Pain and Spinal Nociception in Sexual Assault Survivors.Psychosomatic medicineArticle
- Hypertension and pain: A state-based framework for cardiovascular-nociceptive coupling.Neurobiology of pain (Cambridge, Mass.)Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Supraspinal pain modulation may explain hypertensive hypoalgesia. We compared nociceptive flexion reflex (NFR) thresholds and pain during rest and computer game play in hypertensives and normotensives (Experiment 1) and normotensives with and without hypertensive parents (Experiment 2). The game was selected to modulate activity in pain pathways. NFR thresholds did not differ between groups during rest or game play. Pain ratings never differed between hypertensives and normotensives, whereas individuals with hypertensive parents reported less pain during the first two NFR assessments, compared to those without. NFR thresholds and pain were reduced by game play compared to rest. The failure of game play to differentially modulate NFR thresholds or associated pain reports between groups argues against enhanced supraspinal modulation of nociception and pain in hypertensives and those at increased risk for hypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.