ArticleThe American journal of managed care2007
Adherence to beta-blocker therapy under drug cost-sharing in patients with and without acute myocardial infarction.
Article in The American journal of managed care, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Cost-related medication nonadherence in Canada: a systematic review of prevalence, predictors, and clinical impact.Systematic reviews · 2021Pooled it
- Pharmaceutical policies: effects of cap and co-payment on rational use of medicines.The Cochrane database of systematic reviews · 2015Pooled it
- Association between drug insurance cost sharing strategies and outcomes in patients with chronic diseases: a systematic review.PloS one · 2014Pooled it
- Pooled it
- Universal Pharmacare and Contraceptive Dispensations Among Youth.JAMA pediatrics · 2025Article
- Economic Evidence on Cost Sharing and Alternative Insurance Designs to Address Moral and Behavioral Hazards in High-Income Health Care Systems: A Systematic Review.Journal of market access & health policy · 2024Review
- Patient preferences for medication adherence financial incentive structures: A discrete choice experiment.Research in social & administrative pharmacy : RSAP · 2021Article
- Perceived appropriateness of medication adherence incentives.Journal of managed care & specialty pharmacy · 2021Article
- The Influence of National Health Insurance on Medication Adherence Among Outpatient Type 2 Diabetics in Southwest Nigeria.Journal of patient experience · 2018Article
- Relationships between Medication Adherence and Cardiovascular Disease Risk Factor Control in Elderly Patients with Diabetes.Pharmacotherapy · 2017Article
- Effect of cost sharing on adherence to evidence-based medications in patients with acute coronary syndrome.Heart (British Cardiac Society) · 2017Article
- Universal prescription drug coverage in Canada: Long-promised yet undelivered.Healthcare management forum · 2016Review
- Comparative studies of how living circumstances influence medication adherence in ≥65 year olds.International journal of clinical pharmacy · 2014Review
- Standardizing terminology and definitions of medication adherence and persistence in research employing electronic databases.Medical care · 2013Article
- How patient cost-sharing trends affect adherence and outcomes: a literature review.P & T : a peer-reviewed journal for formulary management · 2012Article
- Does medication adherence following a copayment increase differ by disease burden?Health services research · 2011Article
- Statin adherence and the risk of major coronary events in patients with diabetes: a nested case-control study.British journal of clinical pharmacology · 2011Article
- Adherence to medicines in the older-aged with chronic conditions: does intervention by an allied health professional help?Drugs & aging · 2010Review
- Costs and benefits of free medications after myocardial infarction.Healthcare policy = Politiques de sante · 2009Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo evaluate the effects of patient copayment and coinsurance policies on adherence to therapy with beta-adrenergic blocking agents (beta-blockers) and on the rate of initiation of beta-blocker therapy after acute myocardial infarction (MI) in a population-based natural experiment. STUDY
designThree sequential cohorts included British Columbia residents age 66 years and older who initiated beta-blocker therapy during time intervals with full drug coverage (2001), a $10 or $25 copayment (2002), and 25% coinsurance (2003-2004). We used linked data on all prescription drug dispensings, physician services, and hospitalizations. Follow-up of each cohort was 9 months after the policy changes.
methodsWe measured the proportion of subjects in each cohort who were adherent to beta-blocker therapy over time, with adherence defined as having >80% of days covered. We also measured the proportion of patients initiating beta-blocker therapy after acute MI. Policy effects were evaluated using multivariable regression.
resultsAdherence to beta-blocker therapy was marginally reduced as a consequence of the copayment policy (-1.3 percentage points, 95% confidence interval [CI] = -2.5 , -0.04) or the coinsurance policy (-0.8 percentage points, 95% CI = -2.0, 0.3). The proportion of patients initiating beta-blockers after hospitalization for acute MI remained steady at about 61% during the study period, similar to that observed in a control population of elderly Pennsylvania residents with full drug coverage.
conclusionsFixed patient copayment and coinsurance policies had little negative effect on adherence to relatively inexpensive beta-blocker therapy, or initiation of beta-blockers after acute MI.
Indexed as
Identifiers
17685825PMC2905663W182086655What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.