Evidence map›Paper›PMID 17684745›Full record

ArticleCurrent genetics2007

Identification of a mitotic recombination hotspot on chromosome III of the asexual fungus Aspergillus niger and its possible correlation with [corrected] elevated basal transcription.

Peter J I van de Vondervoort, Sandra M J Langeveld, Jaap Visser, Noël N M E van Peij, Herman J Pel, Cees A M J J van den Hondel, Arthur F J Ram

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Peter J I van de VondervoortInstitute of Biology, Leiden University, Wassenaarseweg 64, 2333 AL Leiden, The Netherlands.
Sandra M J Langeveld
Jaap Visser
Noël N M E van Peij
Herman J Pel
Cees A M J J van den Hondel
Arthur F J Ram
Leiden University · NLDSM (Netherlands) · NLDelft University of Technology · NLWageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic recombination is an important tool in strain breeding in many organisms. We studied the possibilities of mitotic recombination in strain breeding of the asexual fungus Aspergillus niger. By identifying genes that complemented mapped auxotrophic mutations, the physical map was compared to the genetic map of chromosome III using the genome sequence. In a program to construct a chromosome III-specific marker strain by selecting mitotic crossing-over in diploids, a mitotic recombination hotspot was identified. Analysis of the mitotic recombination hotspot revealed some physical features, elevated basal transcription and a possible correlation with purine stretches.

Indexed as

MitosisRecombination, GeneticTranscription, GeneticAspergillus nigerChromosome MappingChromosome SegregationChromosomes, FungalCrossing Over, GeneticDiploidyGenes, FungalGenetic LinkageGenetic MarkersMicroarray AnalysisMutationPurinesGenetic MarkersPurines

Identifiers

PMID17684745
PMCPMC2071955
OpenAlexW1995969120

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.