ArticleBMC neurology2007
Cardiovascular responses to cognitive stress in patients with migraine and tension-type headache.
Article in BMC neurology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 17 citations in OpenAlex.
- Effects of neck-exercise and health promotion on headache outcomes in office workers: secondary analysis of the NEXpro stepped wedge cluster randomised controlled trial.The journal of headache and pain · 2025Trial
- The Four-Cluster Spectrum of Mind-Body Interrelationships: An Integrative Model.Frontiers in psychiatry · 2019Article
- Psychological generators of stress-headaches.Journal of behavioral medicine · 2018Article
- Psychological issues in the evaluation and treatment of tension-type headache.Current pain and headache reports · 2012Review
- Psychological issues in the evaluation and treatment of tension-type headache.Current pain and headache reports · 2008Review
- Similarities in stress physiology among patients with chronic pain and headache disorders: evidence for a common pathophysiological mechanism?The journal of headache and pain · 2008Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to investigate the temporal relationship between autonomic changes and pain activation in migraine and tension-type headache induced by stress in a model relevant for everyday office-work.
methodsWe measured pain, blood pressure (BP), heart rate (HR) and skin blood flow (BF) during and after controlled low-grade cognitive stress in 22 migraineurs during headache-free periods, 18 patients with tension-type headache (TTH) and 44 healthy controls. The stress lasted for one hour and was followed by 30 minutes of relaxation.
resultsCardiovascular responses to cognitive stress in migraine did not differ from those in control subjects. In TTH patients HR was maintained during stress, whereas it decreased for migraineurs and controls. A trend towards a delayed systolic BP response during stress was also observed in TTH. Finger BF recovery was delayed after stress and stress-induced pain was associated with less vasoconstriction in TTH during recovery.
conclusionIt is hypothesized that TTH patients have different stress adaptive mechanisms than controls and migraineurs, involving delayed cardiovascular adaptation and reduced pain control system inhibition.
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Registered trials
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