ReviewJournal of anatomy2007
Contribution of endothelial cells to organogenesis: a modern reappraisal of an old Aristotelian concept.
Review in Journal of anatomy, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 62 citations in OpenAlex.
- hESCs-derived Organoids Achieve Liver Zonation Features through LSEC Modulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- How Delayed Cord Clamping Saves Newborn Lives.Children (Basel, Switzerland) · 2025Review
- A genetically inducible endothelial niche enables vascularization of human kidney organoids with multilineage maturation and emergence of renin expressing cells.Kidney international · 2024Article
- Endothelial cells regulate alveolar morphogenesis by constructing basement membranes acting as a scaffold for myofibroblasts.Nature communications · 2024Article
- Aberrant tumor vasculature. Facts and pitfalls.Frontiers in pharmacology · 2024Review
- Genetically engineering endothelial niche in human kidney organoids enables multilineage maturation, vascularization and de novo cell types.bioRxiv : the preprint server for biology · 2023Article
- The vasculature: a therapeutic target in heart failure?Cardiovascular research · 2022Review
- Engineering the multiscale complexity of vascular networks.Nature reviews. Materials · 2022Review
- The vascular niche in next generation microphysiological systems.Lab on a chip · 2021Review
- Role of Notch in endothelial biology.Angiogenesis · 2021Review
- Review
- Engineering PEG-based hydrogels to foster efficient endothelial network formation in free-swelling and confined microenvironments.Biomaterials · 2020Article
- Endothelial YAP1 in Regenerative Lung Growth through the Angiopoietin-Tie2 Pathway.American journal of respiratory cell and molecular biology · 2019Article
- A perivascular niche for multipotent progenitors in the fetal testis.Nature communications · 2018Article
- Re-evaluating the functional landscape of the cardiovascular system during development.Biology open · 2017Article
- CLARITY reveals dynamics of ovarian follicular architecture and vasculature in three-dimensions.Scientific reports · 2017Article
- Survival of motor neurone protein is required for normal postnatal development of the spleen.Journal of anatomy · 2017Article
- Effective endothelial cell and human pluripotent stem cell interactions generate functional insulin-producing beta cells.Diabetologia · 2016Article
- Review
- Endothelium-derived essential signals involved in pancreas organogenesis.World journal of experimental medicine · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well established that many tissue-derived factors are involved in blood vessel formation, but evidence is now emerging that endothelial cells themselves represent a crucial source of instructive signals to non-vascular tissue cells during organ development. Thus, endothelial cell signalling is currently believed to promote fundamental cues for cell fate specification, embryo patterning, organ differentiation and postnatal tissue remodelling. This review article summarizes some of the recent advances in our understanding of the role of endothelial cells as effector cells in organ formation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.