ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2007
Hospital-based surveillance of meningococcal meningitis in Salvador, Brazil.
Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Diagnosis and Potential Therapy of Brain Diseases UsingCurrent medicinal chemistry · 2026Article
- Effectiveness of meningococcal C conjugate vaccine in Salvador, Brazil: a case-control study.PloS one · 2015Article
- An epidemiological review of changes in meningococcal biology during the last 100 years.Pathogens and global health · 2013Review
- The epidemiology of meningococcal disease in Latin America 1945-2010: an unpredictable and changing landscape.Epidemiology and infection · 2013Review
- Accuracy of real-time PCR, Gram stain and culture for Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae meningitis diagnosis.BMC infectious diseases · 2013Article
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Authors and funding
11 authors.
Funding
Abstract
This study aimed to describe the clinical, epidemiological and microbiological features of meningococcal meningitis in Salvador, Brazil. Between February 1996 and January 2001, a hospital-based surveillance prospectively identified cases of culture-positive meningococcal meningitis. Demographic and clinical data were collected through interview and medical chart review. Antisera and monoclonal antibodies were used to determine the serogroup and serotype:serosubtype of the isolates, respectively. Surveillance identified a total of 408 cases of meningococcal meningitis, with a case fatality rate of 8% (32/397). The mean annual incidence for the 304 culture-positive cases residing in metropolitan Salvador was 1.71 cases per 100,000 population. Infants <1 year old presented the highest incidence (14.7 cases per 100,000 population). Of the 377 serogrouped isolates, 82%, 16%, 2% and 0.3% were serogroups B, C, W135 and Y, respectively. A single serotype:serosubtype (4,7:P1.19,15) accounted for 64% of all cases. Continued surveillance is necessary to characterise strains and to define future prevention and control strategies.
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