ArticleThe international journal of cardiovascular imaging2008
Obesity is associated with aortic enlargement and increased stiffness: an echocardiographic study.
Article in The international journal of cardiovascular imaging, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 34 citations in OpenAlex.
- Differential Deleterious Impact of Highly Saturated Versus Monounsaturated Fat Intake on Vascular Function, Structure, and Mechanics in Mice.Nutrients · 2021Article
- Taurine supplementation prevents endothelial dysfunction and attenuates structural changes in aortas from hypothalamic obese rats.European journal of nutrition · 2019Article
- Beneficial Effect of Bariatric Surgery on Abnormal MMP-9 and AMPK Activities: Potential Markers of Obesity-Related CV Risk.Frontiers in physiology · 2019Article
- Carotid pulse wave velocity by magnetic resonance imaging is increased in middle-aged subjects with the metabolic syndrome.The international journal of cardiovascular imaging · 2015Article
- Obesity and overweight associated with increased carotid diameter and decreased arterial function in young otherwise healthy men.American journal of hypertension · 2014Article
- Observational study of regional aortic size referenced to body size: production of a cardiovascular magnetic resonance nomogram.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2014Observational
- Prevalence of arterial stiffness in North China, and associations with risk factors of cardiovascular disease: a community-based study.BMC cardiovascular disorders · 2012Article
- Vascular function in health and disease review series.Journal of cellular and molecular medicine · 2010Article
- A relationship between echocardiographic subepicardial adipose tissue and metabolic syndrome.The international journal of cardiovascular imaging · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity may be associated with early vascular changes. The current study was designed to assess the relationship between obesity and aortic stiffness in two populations, one aged 18-40 years and one aged 41-64 years.
methodsThe study complied 121 subjects, all of them underwent a physical examination, transthoracic echocardiography and blood pressure measurement. Aortic stiffness index (beta) was evaluated from aortic diameter and blood pressure data.
resultsbeta was higher in obese subjects both in the young (4.26 +/- 1.57 vs. 6.88 +/- 5.96, P < 0.05) and old patient populations (7.13 +/- 4.99 vs. 14.89 +/- 14.64, P < 0.05). Systolic (SD) aortic diameters (in mm) were enlarged in obese young patients (25.7 +/- 2.8 vs. 27.1 +/- 2.5, P < 0.05) and obese old subjects (28.0 +/- 3.0 vs. 30.3 +/- 3.3, P < 0.05). Diastolic (DD) aortic diameter (in mm) showed similar tendency in youngs (22.8 +/- 2.9 vs. 24.9 +/- 2.5, P < 0.05) and old subjects (25.9 +/- 2.7 vs. 28.0 +/- 3.1, P < 0.05).
conclusionsAortic stiffness is higher in young obese patients and similar to older subjects without obesity. Both SD and DD are increasing with age, but subjects within similar age group have larger SD and DD suggesting early vascular remodelling in obesity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.