Evidence map›Paper›PMID 17678718›Full record

ReviewHuman immunology2007

Accommodation of grafts: implications for health and disease.

Amy H Tang, Jeffrey L Platt

Abstract readReview
In one paragraph

Review in Human immunology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Encapsulated cell grafts to treat cellular deficiencies and dysfunction.Critical reviews in biomedical engineering · 2011
    Review
  9. Antibodies in transplantation.Discovery medicine · 2010
    Review
  10. Review
  11. Escaping from rejection.Transplantation · 2009
    Review
  12. Effect of antibodies on endothelium.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2009
    Review
  13. Lessons from cardiac transplantation in infancy.Pediatric transplantation · 2009
    Review
  14. The role of antibodies in transplantation.Transplantation reviews (Orlando, Fla.) · 2009
    Review
  15. Review
  16. B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2009
    Article
  17. Noncognate function of B cells in transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2009
    Review
  18. Report from a consensus conference on the sensitized patient awaiting heart transplantation.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2009
    Article
  19. Article
  20. The anti-non-gal xenoantibody response to xenoantigens on gal knockout pig cells is encoded by a restricted number of germline progenitors.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amy H TangTransplantation Biology, Mayo Clinic College of Medicine, Rochester, MN, USA.
Jeffrey L Platt

Funding

T cell responses and cardiac transplantation in infancyP01HL079067 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PLATT, JEFFREY L · 2005 to 2009
$6.3M
Xenogeneic Natural Antibody Targets-Structure/FunctionR37HL052297 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PLATT, JEFFREY L · 2001 to 2010
$3.9M
XENOGENEIC NATURAL ANTIBODY TARGETS--STRUCTURE/FUNCTIONR01HL052297 · NHLBI · MAYO CLINIC COLL OF MEDICINE, ROCHESTER · PI PLATT, JEFFREY L · 1993 to 2000
$319k
NHLBI NIH HHS HL079067NHLBI NIH HHS HL52297NHLBI NIH HHS P01 HL079067NHLBI NIH HHS R01 HL052297NHLBI NIH HHS R37 HL052297NIGMS NIH HHS GM96922
6 · The paper itself

Abstract

Accommodation refers to the acquired resistance of a graft to immune-mediated injury. It is typically observed after antibodies that would cause rejection of a graft are removed from a recipient and then later return. In addition to being induced in this manner, accommodation can occur spontaneously, without depleting antibodies. Indeed, we postulate spontaneous accommodation may be the most common outcome of clinical organ transplantation. The paper reviews the current understanding of accommodation, emphasizing recent advances and important questions. Among the recent advances are the discoveries of potentially broader relevance of accommodation for biology and immunology and pathways by which accommodation may be achieved. To investigate these pathways and to understand how accommodation begins and how it evolves, clinical organ transplants might offer a useful and incisive model.

Indexed as

ABO Blood-Group SystemAntibodiesGraft RejectionGraft SurvivalHLA AntigensHost vs Graft ReactionHumansImmune ToleranceTransplantation, HomologousABO Blood-Group SystemAntibodiesHLA Antigens

Identifiers

PMID17678718
PMCPMC2703470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.