ArticleApplied and environmental microbiology2007
Novel nickel resistance genes from the rhizosphere metagenome of plants adapted to acid mine drainage.
Article in Applied and environmental microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 130 citations in OpenAlex.
- Diverse microbial metal resistance and novel metal cycling organisms in copper/nickel mine tailings.Metallomics : integrated biometal science · 2026Article
- Bioremoval of lead, cadmium, chromium, and nickel by multi-metal tolerant Kurthia gibsonii ES43G, Kluyvera cryocrescens ES45G and Comamonas aquatica ES54G.Folia microbiologica · 2025Article
- Unveiling Novel Genetic Loci and Superior Alleles for Nickel Accumulation in Wheat via Genome-Wide Association Study.Plants (Basel, Switzerland) · 2025Article
- The First Inventory of Sardinian Mining Vascular Flora.Plants (Basel, Switzerland) · 2025Article
- Meta-omics assisted microbial gene and strain resources mining in contaminant environment.Engineering in life sciences · 2024Review
- Using Mediterranean Native Plants for the Phytoremediation of Mining Sites: An Overview of the Past and Present, and Perspectives for the Future.Plants (Basel, Switzerland) · 2023Review
- Emerging enzyme surface display systems for waste resource recovery.Environmental microbiology · 2023Review
- Isolation of novel cold-tolerance genes from rhizosphere microorganisms of Antarctic plants by functional metagenomics.Frontiers in microbiology · 2022Article
- Mining for Perchlorate Resistance Genes in Microorganisms From Sediments of a Hypersaline Pond in Atacama Desert, Chile.Frontiers in microbiology · 2021Article
- Novel Genes Involved in Resistance to Both Ultraviolet Radiation and Perchlorate From the Metagenomes of Hypersaline Environments.Frontiers in microbiology · 2020Article
- Boundaries in metagenomic screenings using lacZα-based vectors.Genetics and molecular biology · 2020Article
- Comparative Analyses of the Microbial Communities Inhabiting Coal Mining Waste Dump and an Adjacent Acid Mine Drainage Creek.Microbial ecology · 2019Article
- The Heavy-Metal Resistance Determinant of Newly Isolated Bacterium from a Nickel-Contaminated Soil in Southwest Slovakia.Polish journal of microbiology · 2018Article
- Article
- Metagenomic Approaches for Understanding New Concepts in Microbial Science.International journal of genomics · 2018Review
- Metagenomics and Bioinformatics in Microbial Ecology: Current Status and Beyond.Microbes and environments · 2016Review
- Long-term nickel exposure altered the bacterial community composition but not diversity in two contrasting agricultural soils.Environmental science and pollution research international · 2015Article
- Salt resistance genes revealed by functional metagenomics from brines and moderate-salinity rhizosphere within a hypersaline environment.Frontiers in microbiology · 2015Article
- The study of Nickel Resistant Bacteria (NiRB) isolated from wastewaters polluted with different industrial sources.Journal of environmental health science & engineering · 2014Article
- Microbial enzymes: tools for biotechnological processes.Biomolecules · 2014Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metal resistance determinants have traditionally been found in cultivated bacteria. To search for genes involved in nickel resistance, we analyzed the bacterial community of the rhizosphere of Erica andevalensis, an endemic heather which grows at the banks of the Tinto River, a naturally metal-enriched and extremely acidic environment in southwestern Spain. 16S rRNA gene sequence analysis of rhizosphere DNA revealed the presence of members of five phylogenetic groups of Bacteria and the two main groups of Archaea mostly associated with sites impacted by acid mine drainage (AMD). The diversity observed and the presence of heavy metals in the rhizosphere led us to construct and screen five different metagenomic libraries hosted in Escherichia coli for searching novel nickel resistance determinants. A total of 13 positive clones were detected and analyzed. Insights about their possible mechanisms of resistance were obtained from cellular nickel content and sequence similarities. Two clones encoded putative ABC transporter components, and a novel mechanism of metal efflux is suggested. In addition, a nickel hyperaccumulation mechanism is proposed for a clone encoding a serine O-acetyltransferase. Five clones encoded proteins similar to well-characterized proteins but not previously reported to be related to nickel resistance, and the remaining six clones encoded hypothetical or conserved hypothetical proteins of uncertain functions. This is the first report documenting nickel resistance genes recovered from the metagenome of an AMD environment.
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