Evidence map›Paper›PMID 17675391›Full record

ArticleSexually transmitted infections2007

Risk factors for syphilis infection among pregnant women: results of a case-control study in Shenzhen, China.

Hua Zhou, Xiang-Sheng Chen, Fu-Chang Hong, Peng Pan, Fan Yang, Yu-Mao Cai, Yue-Ping Yin, Rosanna W Peeling, David Mabey

Open access · bronzeAbstract read
In one paragraph

Article in Sexually transmitted infections, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Antibiotics for syphilis diagnosed during pregnancy.The Cochrane database of systematic reviews · 2001
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  10. Synthesized prevention and control of one decade for mother-to-child transmission of syphilis and determinants associated with congenital syphilis and adverse pregnancy outcomes in Shenzhen, South China.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014
    Article
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  12. Maternal and paternal factors associated with congenital syphilis in Shenzhen, China: a prospective cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Hua ZhouInstitute of Dermatology, Shenzhen Chronic Disease Hospital, Shenzhen, China.
Xiang-Sheng Chen
Fu-Chang Hong
Peng Pan
Fan Yang
Yu-Mao Cai
Yue-Ping Yin
Rosanna W Peeling
David Mabey
Shenzhen Chronic Disease Prevention Center · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNLondon School of Hygiene & Tropical Medicine · GBWorld Health Organization · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChina has been experiencing a rapidly growing syphilis epidemic since the early 1990s, with the reported incidence of congenital syphilis increasing from 0.01 cases per 100,000 live births in 1991 to 19.7 cases per 100,000 live births in 2005. Detailed studies of risk factors for syphilis in pregnant women are needed to inform new preventive interventions.

objectiveTo investigate factors associated with recent syphilis infection among pregnant women and recommend strategies for improved preventive interventions in the community.

methodsA case-control study was conducted among women attending antenatal clinics in Shenzhen City, South China. Cases were antenatal clinic women testing positive for early syphilis, based on laboratory results, with those testing negative being controls. All participants completed the same anonymous questionnaire covering demographics, lifestyle, sexual behaviour, and sexual partnerships.

results129 cases and 345 controls were recruited. Syphilis was significantly associated with unmarried status, less education, multiple sex partners, travel of sex partner in the past 12 months, a history of induced abortion, and previous sexually transmitted infections. Overall, there were no differences between syphilis-positive and negative women in household registration status (hukou), living district and duration in Shenzhen, monthly income, and age at first sex.

conclusionsMany demographic and behavioural risk factors are associated with syphilis among pregnant women. In the government congenital syphilis control programme, comprehensive preventive interventions should be provided in all clinical settings in addition to the current procedures for syphilis screening among antenatal women.

Indexed as

AdultCase-Control StudiesChinaDelivery, ObstetricFemaleHumansMaternal Health ServicesPregnancyPregnancy Complications, InfectiousRisk FactorsSyphilis

Identifiers

PMID17675391
PMCPMC2598725
OpenAlexW2085619225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.