Evidence map›Paper›PMID 17675260›Full record

ReviewInternational journal of hematology2007

Mesenchymal stem cells in cancer: tumor-associated fibroblasts and cell-based delivery vehicles.

Brett Hall, Jennifer Dembinski, A Kate Sasser, Matus Studeny, Michael Andreeff, Frank Marini

Abstract readReview
PubMed Publisher
In one paragraph

Review in International journal of hematology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Effect of using different co-ligands duringIranian journal of basic medical sciences · 2021
    Article
  5. Review
  6. Review
  7. Article
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  12. The Dynamic Roles of Mesenchymal Stem Cells in Colon Cancer.Canadian journal of gastroenterology & hepatology · 2018
    Review
  13. Article
  14. Article
  15. Article
  16. Mesenchymal stem cells as a double-edged sword in suppression or progression of solid tumor cells.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Review
  17. Article
  18. Article
  19. Article
  20. Stem cell technology in breast cancer: current status and potential applications.Stem cells and cloning : advances and applications · 2016
    Review

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brett HallDepartment of Pediatrics, The Ohio State University and Center for Childhood Cancer, Columbus Children's Research Institute, Columbus, OH, USA.
Jennifer Dembinski
A Kate Sasser
Matus Studeny
Michael Andreeff
Frank Marini

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent evidence suggests that mesenchymal stem cells (MSC) selectively home to tumors, where they contribute to the formation of tumor-associated stroma. This effect can be opposed by genetically modifying MSC to produce high levels of anti-cancer agents that blunt tumor growth kinetics and inhibit the growth of tumors in situ. In this review article, we describe the biological properties of MSC within the tumor microenvironment and discuss the potential use of MSC and other bone marrow-derived cell populations as delivery vehicles for antitumor proteins.

Indexed as

AnimalsExtracellular MatrixFibroblastsGenetic TherapyHumansMesenchymal Stem CellsMesenchymal Stem Cell TransplantationNeoplasms

Identifiers

PMID17675260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.