ArticleGenes & development2007
The PAS/LOV protein VIVID controls temperature compensation of circadian clock phase and development in Neurospora crassa.
Article in Genes & development, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed.
- Enhancing the performance of Magnets photosensors.Nature communications · 2026Article
- A Single-Component Optogenetic Gal4-UAS System Allows Stringent Control of Gene Expression in Zebrafish and Drosophila.ACS synthetic biology · 2023Article
- Data-driven modelling captures dynamics of the circadian clock of Neurospora crassa.PLoS computational biology · 2022Article
- Temperature-responsive optogenetic probes of cell signaling.Nature chemical biology · 2022Article
- Engineering AraC to make it responsive to light instead of arabinose.Nature chemical biology · 2021Article
- Engineering Photosensory Modules of Non-Opsin-Based Optogenetic Actuators.International journal of molecular sciences · 2020Review
- Blakeslea trispora Photoreceptors: Identification and Functional Analysis.Applied and environmental microbiology · 2020Article
- No Evidence That Homologs of Key Circadian Clock Genes Direct Circadian Programs of Development or mRNA Abundance inFrontiers in microbiology · 2020Article
- High-performance chemical- and light-inducible recombinases in mammalian cells and mice.Nature communications · 2019Article
- Light induces oxidative damage and protein stability in the fungal photoreceptor Vivid.PloS one · 2018Article
- Up-Frameshift Protein UPF1 RegulatesGenetics · 2017Article
- Dissecting the mechanisms of the clock in Neurospora.Methods in enzymology · 2015Review
- The Neurospora photoreceptor VIVID exerts negative and positive control on light sensing to achieve adaptation.Molecular systems biology · 2013Article
- Light-inducible system for tunable protein expression in Neurospora crassa.G3 (Bethesda, Md.) · 2012Article
- Temperature-sensitive and circadian oscillators of Neurospora crassa share components.Genetics · 2012Article
- Comprehensive modelling of the Neurospora circadian clock and its temperature compensation.PLoS computational biology · 2012Article
- Adaptive temperature compensation in circadian oscillations.PLoS computational biology · 2012Article
- The circadian clock of Neurospora crassa.FEMS microbiology reviews · 2012Review
- Neurospora crassa Light Signal Transduction Is Affected by ROS.Journal of signal transduction · 2012Article
- Neurospora illuminates fungal photoreception.Fungal genetics and biology : FG & B · 2010Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Circadian clocks are cellular timekeepers that regulate aspects of temporal organization on daily and seasonal time scales. To allow accurate time measurement, the period lengths of clocks are conserved in a range of temperatures--a phenomenon known as temperature compensation. Temperature compensation of circadian clock period aids in maintaining a stable "target time" or phase of clock-controlled events. Here we show that the Neurospora protein VIVID (VVD) buffers the circadian system against temperature fluctuations. In vvd-null mutants, the circadian period of clock-controlled events such as asexual sporulation (conidiation) is temperature compensated, but the phase of this clock time marker is not. Consistent with delayed conidiation at lower temperatures in vvd(KO) strains, the levels of vvd gene products in the wild type increase with decreasing temperatures. Moreover, vvd(C108A) mutants that lack the light function of VVD maintain a dark activity that transiently influences the phase of conidiation, indicating that VVD influences the time of conidiation downstream from the clock. FREQUENCY (FRQ) phosphorylation is altered in a vvd(KO) strain, suggesting a mechanism by which VVD can influence the timing of clock-controlled processes in the dark. Thus, temperature compensation of clock-controlled output is a key factor in maintaining temperature compensation of the entire circadian system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.