Evidence map›Paper›PMID 17670933›Full record

ArticleJournal of clinical microbiology2007

Potential of a simplified p24 assay for early diagnosis of infant human immunodeficiency virus type 1 infection in Haiti.

Erik George, Carole Anne Beauharnais, Emilio Brignoli, Francine Noel, Gyrlande Bois, Patricia De Matteis Rouzier, Martine Altenor, Daniel Lauture, Marlène Hosty, Sapna Mehta and 2 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Point of care testing for infectious diseases.Clinica chimica acta; international journal of clinical chemistry · 2019
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Analysis of the optimal cut-point for HIV-p24 antigen testing to diagnose HIV infection in HIV-exposed children from resource-constrained settings.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2011
    Article
  9. Article
  10. Using a simplified human immunodeficiency virus type 1 p24 antigen assay to diagnose pediatric HIV-infection in Malawi.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2010
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Erik GeorgeDepartment of Medicine, Weill Medical College, Cornell University, New York, NY, USA. erikgeorge@yepmail.net
Carole Anne Beauharnais
Emilio Brignoli
Francine Noel
Gyrlande Bois
Patricia De Matteis Rouzier
Martine Altenor
Daniel Lauture
Marlène Hosty
Sapna Mehta
Peter F Wright
Jean W Pape
Gheskio Centers · HTVanderbilt University · USCornell University · US

Funding

Haiti AIDS Research Training: Models to ImplementationU2RTW006896 · FIC · GHESKIO CENTER · PI PAPE, JEAN WILLIAM · 2004 to 2013
$5.1M
HAITI AIDS RESEARCH TRAINING: MODELS TO IMPLEMENTATIONU2RTW006901 · FIC · WEILL MEDICAL COLL OF CORNELL UNIV · PI JOHNSON, WARREN DOUGLAS · 2004 to 2009
$1.1M
FIC NIH HHS TW006896FIC NIH HHS TW006901
6 · The paper itself

Abstract

With global efforts to scale up the prevention of mother-to-child transmission services and pediatric antiretroviral therapy, there is an urgent need to introduce a simple, low-cost infant human immunodeficiency virus test in the field. We postulated that the p24 antigen capture enzyme-linked immunosorbent assay could be simplified by eliminating signal amplification without compromising diagnostic accuracy.

Indexed as

HIV-1Acquired Immunodeficiency SyndromeEarly DiagnosisEnzyme-Linked Immunosorbent AssayHIV Core Protein p24HumansInfant, NewbornRNA, ViralSensitivity and SpecificityHIV Core Protein p24RNA, Viral

Identifiers

PMID17670933
PMCPMC2045325
OpenAlexW2118311382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.