ArticleNucleic acids research2007
Targeted high-throughput sequencing of tagged nucleic acid samples.
Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
82 citing papers in PubMed.
- The genetic landscape of northeastern Iberian communities from the early to late Iron Age.iScience · 2026Article
- Compositional Changes and Comparative Analysis of Oral Microbial Community During the Formation of Canine Dental Calculus.Animals : an open access journal from MDPI · 2025Article
- Genetic transitions in the Neolithic and Bronze Age at Mas d'en Boixos (Catalonia, Spain).iScience · 2025Article
- Ancient DNA challenges prevailing interpretations of the Pompeii plaster casts.Current biology : CB · 2024Article
- AmpliSAS and AmpliHLA: Web Server and Local Tools for MHC Typing of Non-model Species and Human Using NGS Data.Methods in molecular biology (Clifton, N.J.) · 2024Article
- On the functional relevance of spatiotemporally-specific patterns of experience-dependent long noncoding RNA expression in the brain.RNA biology · 2021Review
- Targeted deep sequencing revealed variants in cell-free DNA of hormone receptor-positive metastatic breast cancer patients.Cellular and molecular life sciences : CMLS · 2020Article
- Prevalence of Ineffective Haplotypes at the Rice Blast Resistance (R) Gene Loci in Chinese Elite Hybrid Rice Varieties Revealed by Sequence-Based Molecular Diagnosis.Rice (New York, N.Y.) · 2020Article
- Whole-Genome Sequencing of Yeast Cells.Current protocols in molecular biology · 2019Article
- An efficient and cost-effective method for primer-induced nucleotide labeling for massive sequencing on next-generation sequencing platforms.Scientific reports · 2019Article
- Article
- Unraveling long non-coding RNAs through analysis of high-throughput RNA-sequencing data.Non-coding RNA research · 2017Review
- Article
- The ability of human nuclear DNA to cause false positive low-abundance heteroplasmy calls varies across the mitochondrial genome.BMC genomics · 2016Article
- Capturing Darwin's dream.Molecular ecology resources · 2016Article
- Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus.American journal of physical anthropology · 2016Article
- Article
- A comprehensive benchmarking study of protocols and sequencing platforms for 16S rRNA community profiling.BMC genomics · 2016Article
- SV-STAT accurately detects structural variation via alignment to reference-based assemblies.Source code for biology and medicine · 2016Article
- Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm.Nature protocols · 2015Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-throughput 454 DNA sequencing technology allows much faster and more cost-effective sequencing than traditional Sanger sequencing. However, the technology imposes inherent limitations on the number of samples that can be processed in parallel. Here we introduce parallel tagged sequencing (PTS), a simple, inexpensive and flexible barcoding technique that can be used for parallel sequencing any number and type of double-stranded nucleic acid samples. We demonstrate that PTS is particularly powerful for sequencing contiguous DNA fragments such as mtDNA genomes: in theory as many as 250 mammalian mtDNA genomes can be sequenced in a single GS FLX run. PTS dramatically increases the sequencing throughput of samples in parallel and thus fully mobilizes the resources of the 454 technology for targeted sequencing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.