ArticleJournal of neurology2007
Systemic risk score evaluation in ischemic stroke patients (SCALA): a prospective cross sectional study in 85 German stroke units.
Article in Journal of neurology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 43 citations in OpenAlex.
- Peripheral Artery Disease in Asian Ischaemic Stroke Patients-A Cross-Sectional Study.NeuroSci · 2026Article
- Assessment of associations between neutrophil extracellular trap biomarkers in blood and thrombi in acute ischemic stroke patients.Journal of thrombosis and thrombolysis · 2024Article
- Development and internal validation of machine learning-based models and external validation of existing risk scores for outcome prediction in patients with ischaemic stroke.European heart journal. Digital health · 2024Article
- The Predictive Value of Essen and SPI-II on the Risk of 5-Year Recurrence in Chinese Patients with Acute Ischemic Stroke.Neuropsychiatric disease and treatment · 2023Article
- Is the TOAST Classification Suitable for Use in Personalized Medicine in Ischemic Stroke?Journal of personalized medicine · 2022Article
- Prevalence of Lower Extremity Arterial Disease as Measured by Low Ankle-Brachial Index in Patients with Acute Cerebral Ischemic Events.Journal of clinical medicine · 2020Article
- Essen Stroke Risk Score Predicts Carotid Atherosclerosis in Chinese Community Populations.Risk management and healthcare policy · 2020Article
- Monocyte Subsets and Related Chemokines in Carotid Artery Stenosis and Ischemic Stroke.International journal of molecular sciences · 2016Article
- High-sensitivity troponin assay improves prediction of cardiovascular risk in patients with cerebral ischaemia.Journal of neurology, neurosurgery, and psychiatry · 2013Article
- [Difficult decisions in stroke therapy].Der Nervenarzt · 2011Review
- Update of secondary stroke prevention.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2009Review
- Predictive value of the Essen Stroke Risk Score and Ankle Brachial Index in acute ischaemic stroke patients from 85 German stroke units.Journal of neurology, neurosurgery, and psychiatry · 2008Article
- Cardiovascular protection for all individuals at high risk: evidence-based best practice.Clinical research in cardiology : official journal of the German Cardiac Society · 2008Review
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeStratification of patients with transient ischemic attack (TIA) or ischemic stroke (IS) by risk of recurrent stroke can contribute to optimized secondary prevention. We therefore aimed to assess cardiovascular risk factor profiles of consecutive patients hospitalized with TIA/IS to stratify the risk of recurrent stroke according to the Essen Stroke Risk Score (ESRS) and of future cardiovascular events according to the ankle brachial index (ABI) as a marker of generalized atherosclerosis
methodsIn this cross-sectional observational study, 85 neurological stroke units throughout Germany documented cardiovascular risk factor profiles of 10 consecutive TIA/IS patients on standardized questionnaires. Screening for PAD was done with Doppler ultrasonography to calculate the ABI.
resultsA total of 852 patients (57% men) with a mean age of 67+/-12.4 years were included of whom 82.9 % had IS. The median National Institutes of Health stroke sum score was 4 (TIA: 1). Arterial hypertension was reported in 71%, diabetes mellitus in 26%, clinical PAD in 10%, and an ABI < or = 0.9 in 51%. An ESRS > or = 3 was observed in 58%, which in two previous retrospective analyses corresponded to a recurrent stroke risk of > or = 4%/year. The correlation between the ESRS and the ABI was low (r = 0.21).
conclusionA high proportion of patients had asymptomatic atherosclerotic disease and a considerable risk of recurrent stroke according to the ABI and ESRS category. The prognostic accuracy as well as the potential benefit of various risk stratification scores in secondary stroke prevention require validation in a larger prospective study.
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