ArticleEuropean journal of applied physiology2007
Alterations of immunoendocrine responses during the recovery period after acute prolonged cycling.
Article in European journal of applied physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Acute and chronic effects of physical exercise on IgA and IgG levels and susceptibility to upper respiratory tract infections: a systematic review and meta-analysis.Pflugers Archiv : European journal of physiology · 2022Pooled it
- Effect of Acute and Chronic Aerobic Exercise on Immunological Markers: A Systematic Review.Frontiers in physiology · 2019Pooled it
- Effects of acute bovine colostrum supplementation on immune responses to prolonged cycling: a randomised crossover trial.European journal of nutrition · 2026Trial
- The effect of aerobic exercise on immune biomarkers and symptoms severity and progression in patients with COVID-19: A randomized control trial.Journal of bodywork and movement therapies · 2021Trial
- The effect of acute pre-exercise dark chocolate consumption on plasma antioxidant status, oxidative stress and immunoendocrine responses to prolonged exercise.European journal of nutrition · 2012Trial
- Cognitive awareness of carbohydrate intake does not alter exercise-induced lymphocyte apoptosis.Clinics (Sao Paulo, Brazil) · 2011Trial
- Intensive physical training induces NET release in athletes.Scientific reports · 2025Article
- Role of Enhancing Aerobic Capacity in Countering COVID-19-induced Liver Injury in Elderlies.Endocrine, metabolic & immune disorders drug targets · 2024Review
- Neurocognitive effects of stress: a metaparadigm perspective.Molecular psychiatry · 2023Review
- Enhancing oxygenation of patients with coronavirus disease 2019: Effects on immunity and other health-related conditions.World journal of clinical cases · 2021Review
- Can Exercise-Induced Muscle Damage Be a Good Model for the Investigation of the Anti-Inflammatory Properties of Diet in Humans?Biomedicines · 2021Review
- Immunomodulation From Moderate Exercise Promotes Control of Experimental Cutaneous Leishmaniasis.Frontiers in cellular and infection microbiology · 2019Article
- Role of increasing the aerobic capacity on improving the function of immune and respiratory systems in patients with coronavirus (COVID-19): A review.Diabetes & metabolic syndromeReview
- Transcriptional control of complement activation in an exercise model of chronic fatigue syndrome.Molecular medicine (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to determine the timecourse of recovery of immunoendocrine responses following prolonged cycling. With the approval of the Ethics Committee, ten healthy men (age 21.6+/-0.9 years, height 1.77+/-0.01 m, body mass 66.9+/-1.8 kg, VO2max 54.2+/-2.0 ml kg(-1) min(-1); means+/-SEM) performed either a 2 h cycling trial at 55% peak aerobic power or a resting control trial in a counterbalanced order, separated by at least 6 days. No food was consumed, though water ingestion was allowed ad libitum, until trials were completed. Venous blood samples were collected at pre-exercise, post-exercise, and at 1, 3, 6 and 9 h post-exercise. Haematological analysis was performed using an automated cell counter. Plasma concentrations of hormones were determined using ELISA kits. Neutrophil degranulation (bacteria-stimulated) and oxidative burst (formyl-methionyl-leucyl-phenylalanine-induced) were measured using an ELISA kit and a chemiluminescence assay, respectively. Results were analyzed using two-factor repeated measures ANOVA with post hoc Tukey tests and paired t tests applied where appropriate. The main findings of this study were that, compared with the resting trial, an acute single bout of prolonged exercise (1) decreased plasma glucose concentrations but increased circulating leukocyte, neutrophil, and monocyte counts for 9 h; (2) increased plasma cortisol concentrations but suppressed neutrophil function on a per cell basis for 6 h. In conclusion, the findings of this study suggest that the impact of a single bout of prolonged cycling on immunoendocrine responses would be recovered around 9 h post-exercise at fasted status.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.