ArticleWorld journal of surgery2007
Surgical treatment of tertiary hyperparathyroidism: the choice of procedure matters!
Article in World journal of surgery, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 74 citations in OpenAlex.
- Total parathyroidectomy versus total parathyroidectomy with autotransplantation for refractory secondary hyperparathyroidism: short-term biochemical outcomes and postoperative calcium supplementation burden.BMC endocrine disorders · 2026Article
- Article
- Review
- Back to my future: life after surgery for tertiary hyperparathyroidism.Langenbeck's archives of surgery · 2024Article
- Surgical treatment of tertiary hyperparathyroidism: does one fit for all?Frontiers in endocrinology · 2023Article
- Impact of parathyroidectomy on kidney graft function in post-transplant tertiary hyperparathyroidism: a comparative study.Langenbeck's archives of surgery · 2022Article
- Acute and long-term kidney function after parathyroidectomy for primary hyperparathyroidism.PloS one · 2020Article
- How radical is total parathyroidectomy in patients with renal hyperparathyroidism?Langenbeck's archives of surgery · 2018Article
- Surgical management of secondary hyperparathyroidism: how to effectively reduce recurrence at the time of primary surgery.Journal of endocrinological investigation · 2016Review
- Characteristics of Persistent Hyperparathyroidism After Renal Transplantation.World journal of surgery · 2016Article
- Analgesic efficacy of bilateral superficial and deep cervical plexus block in patients with secondary hyperparathyroidism due to chronic renal failure.Annals of surgical treatment and research · 2015Article
- Surgical management of secondary hyperparathyroidism in chronic kidney disease--a consensus report of the European Society of Endocrine Surgeons.Langenbeck's archives of surgery · 2015Review
- The calcitonin levels can sometimes mislead parathyroid surgeons in patients with chronic kidney disease and renal hyperparathyroidism: report of a case.Surgery today · 2013Article
- The surgical management of renal hyperparathyroidism.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2012Review
- Initial parathyroid surgery in 606 patients with renal hyperparathyroidism.World journal of surgery · 2012Article
- Total parathyroidectomy without autotransplantation after renal transplantation for tertiary hyperparathyroidism: long-term follow-up.International urology and nephrology · 2012Article
- Parathyroidectomy after kidney transplantation: short-and long-term impact on renal function.Clinics (Sao Paulo, Brazil) · 2011Article
- [Indications for parathyroidectomy in renal hyperparathyroidism: comments on the significance of new therapeutics].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2010Review
- CT-MIBI-SPECT image fusion predicts multiglandular disease in hyperparathyroidism.Langenbeck's archives of surgery · 2010Article
- Minimally invasive video-assisted subtotal parathyroidectomy with thymectomy for secondary hyperparathyroidism.Langenbeck's archives of surgery · 2009Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundParathyroid surgery (PTX) in patients with tertiary hyperparathyroidism (tHPT) may endanger the long-term survival of transplanted renal grafts. The mechanism by which graft function deteriorates is unknown. We reviewed our experience in regard to the operative procedures and postoperative outcome.
methodsSixty-nine patients were operated on for tHPT between 1987 and 2006 at our institution. Serum (s) calcium, s-creatinine, and levels of intact parathyroid hormone (PTH) were measured before and after PTX. The Modification of Diet in Renal Disease (MDRD) equation was used to estimate glomerular filtration rate (GFR).
resultsThe entire patient group developed a deterioration of kidney graft function after PTX. Nineteen of 69 patients developed a decrease in GFR of more than 20% during the hospital stay, persisting for more than one year after PTX. Ten of them had to restart dialysis during the first year after PTX. Mean preoperative s-creatinine was 4.4 +/- 0.6 mg/dl in these patients. When divided according to the surgical procedure performed, only the subgroup who underwent total parathyroidectomy showed a significant worsening of graft function when compared to subtotal or reoperative PTX.
conclusionsPTX is an efficient way to treat tHPT but represents a risk for impairing graft function, especially for patients that already demonstrate poor kidney function at the time of surgery. In the aim to prevent transient hypoparathyroidism, which may provoke reduced graft perfusion, as one possible cause of kidney graft deterioration associated with PTX, one should consider subtotal instead of total parathyroidectomy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.