ArticleProceedings of the National Academy of Sciences of the United States of America2007
Single-molecule fluorescence spectroscopy in (bio)catalysis.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Evidence of a Three-State Mechanism in DNA Hairpin Folding.Journal of the American Chemical Society · 2025Article
- Amalgamation of DNAzymes and Nanozymes in a Coronazyme.Journal of the American Chemical Society · 2023Article
- Theoretical Tools to Quantify Stochastic Fluctuations in Single-Molecule Catalysis by Enzymes and Nanoparticles.ACS omega · 2022Review
- Super-resolution Microscopy with Single Molecules in Biology and Beyond-Essentials, Current Trends, and Future Challenges.Journal of the American Chemical Society · 2020Review
- Optical monitoring of polymerizations in droplets with high temporal dynamic range.Chemical science · 2020Article
- Single-molecule photoredox catalysis.Chemical science · 2019Article
- Communicating catalysts.Nature chemistry · 2018Article
- Computationally Efficient Modelling of Stochastic Spatio-Temporal Dynamics in Biomolecular Networks.Scientific reports · 2018Article
- Rationalizing Acid Zeolite Performance on the Nanoscale by Correlative Fluorescence and Electron Microscopy.ACS catalysis · 2017Article
- Observing Single-Molecule Dynamics at Millimolar Concentrations.Angewandte Chemie (International ed. in English) · 2017Article
- Quantitative 3D Fluorescence Imaging of Single Catalytic Turnovers Reveals Spatiotemporal Gradients in Reactivity of Zeolite H-ZSM-5 Crystals upon Steaming.Journal of the American Chemical Society · 2015Article
- Article
- Shedding light on protein folding, structural and functional dynamics by single molecule studies.Molecules (Basel, Switzerland) · 2014Review
- Enzyme molecules in solitary confinement.Molecules (Basel, Switzerland) · 2014Review
- Super-resolution molecular and functional imaging of nanoscale architectures in life and materials science.Frontiers in bioengineering and biotechnology · 2014Review
- Heterogeneities of individual catalyst particles in space and time as monitored by spectroscopy.Nature chemistry · 2012Review
- Contrasting the individual reactive pathways in protein unfolding and disulfide bond reduction observed within a single protein.Journal of the American Chemical Society · 2011Article
- Probing static disorder in Arrhenius kinetics by single-molecule force spectroscopy.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Oligonucleotide-stabilized Ag nanocluster fluorophores.Journal of the American Chemical Society · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ever-improving time and space resolution and molecular detection sensitivity of fluorescence microscopy offer unique opportunities to deepen our insights into the function of chemical and biological catalysts. Because single-molecule microscopy allows for counting the turnover events one by one, one can map the distribution of the catalytic activities of different sites in solid heterogeneous catalysts, or one can study time-dependent activity fluctuations of individual sites in enzymes or chemical catalysts. By experimentally monitoring individuals rather than populations, the origin of complex behavior, e.g., in kinetics or in deactivation processes, can be successfully elucidated. Recent progress of temporal and spatial resolution in single-molecule fluorescence microscopy is discussed in light of its impact on catalytic assays. Key concepts are illustrated regarding the use of fluorescent reporters in catalytic reactions. Future challenges comprising the integration of other techniques, such as diffraction, scanning probe, or vibrational methods in single-molecule fluorescence spectroscopy are suggested.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.