ArticleThe Plant journal : for cell and molecular biology2007
Salt stress responses in Arabidopsis utilize a signal transduction pathway related to endoplasmic reticulum stress signaling.
Article in The Plant journal : for cell and molecular biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 204 papers, 1 of them a synthesis that pooled it.
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Who cites it
204 citing papers in PubMed, 1 synthesis or guideline pooled it, 462 citations in OpenAlex.
- Cell Death Signaling From Endoplasmic Reticulum Stress: Plant-Specific and Conserved Features.Frontiers in plant science · 2022Pooled it
- Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant-Pathogen Interface.Plant biotechnology journal · 2026Review
- Rewiring the unfolded protein response for plant growth recovery after stress.Plant communications · 2026Review
- Integrated transcriptomic and metabolomic analysis reveals the salt tolerance mechanisms in Lagerstroemia indica.BMC plant biology · 2026Article
- Transcription factor LchiTCP1 modulates abiotic stress response in arabidopsis.Functional & integrative genomics · 2026Article
- Plant cell wall remodeling and peptide signaling under abiotic and biotic stress.Plant communications · 2026Review
- Transcriptome analysis coupled with virus induced gene silencing delineates the unfolded protein response of tomato.Molecular genetics and genomics : MGG · 2026Article
- Integrated transcriptomic and hormonal analysis suggests a trade-off between salt/drought tolerance and thermotolerance inFrontiers in plant science · 2026Article
- Four guidelines to identify bona fide protease-substrate pairs.Journal of experimental botany · 2025Review
- The endoplasmic reticulum-associated degradation machinery selectively degrades stress-induced TIN1 during stress recovery.Plant physiology · 2025Article
- Cloning and Functional Analysis ofPlants (Basel, Switzerland) · 2025Article
- The bZIP transcription factor RISBZ1 balances grain filling and ER stress response in rice grains.Plant communications · 2025Article
- Long-Term Phytaspase Responses inInternational journal of molecular sciences · 2025Article
- Priming thermotolerance: unlocking heat resilience for climate-smart crops.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Article
- The core morning clock component CCA1 enhances UPR target gene expression to facilitate ER stress recovery.Plant communications · 2025Article
- Geminivirus βV1 protein activates bZIP17/28-mediated UPR signaling to facilitate viral pathogenicity but its activity is attenuated by autophagic degradation in plants.Plant communications · 2025Article
- SOS2 phosphorylates FREE1 to regulate multi-vesicular body trafficking and vacuolar dynamics under salt stress.The Plant cell · 2025Article
- Identification and Network Construction of mRNAs, miRNAs, lncRNAs, and circRNAs in Sweetpotato (International journal of molecular sciences · 2025Article
- Review
144 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe a signaling pathway that mediates salt stress responses in Arabidopsis. The response is mechanistically related to endoplasmic reticulum (ER) stress responses described in mammalian systems. Such responses involve processing and relocation to the nucleus of ER membrane-associated transcription factors to activate stress response genes. The salt stress response in Arabidopsis requires a subtilisin-like serine protease (AtS1P), related to mammalian S1P and a membrane-localized b-ZIP transcription factor, AtbZIP17, a predicted type-II membrane protein with a canonical S1P cleavage site on its lumen-facing side and a b-ZIP domain on its cytoplasmic side. In response to salt stress, it was found that myc-tagged AtbZIP17 was cleaved in an AtS1P-dependent process. To show that AtS1P directly targets AtbZIP17, cleavage was also demonstrated in an in vitro pull-down assay with agarose bead-immobilized AtS1P. Under salt stress conditions, the N-terminal fragment of AtbZIP17 tagged with GFP was translocated to the nucleus. The N-terminal fragment bearing the bZIP DNA binding domain was also found to possess transcriptional activity that functions in yeast. In Arabidopsis, AtbZIP17 activation directly or indirectly upregulated the expression of several salt stress response genes, including the homeodomain transcription factor ATHB-7. Upregulation of these genes by salt stress was blocked by T-DNA insertion mutations in AtS1P and AtbZIP17. Thus, salt stress induces a signaling cascade involving the processing of AtbZIP17, its translocation to the nucleus and the upregulation of salt stress genes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.