ArticleGenetics2007
Genetic analysis of dauer formation in Caenorhabditis briggsae.
Article in Genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 41 citations in OpenAlex.
- Caenorhabditis diversity on Pohnpei, Micronesia, provides evidence that the Elegans Supergroup has its roots in the Americas and diversified in the Pacific en route to Asia.Evolution; international journal of organic evolution · 2026Article
- Article
- Heat tolerance and genetic adaptations in Caenorhabditis briggsae: insights from comparative studies with Caenorhabditis elegans.Genetics · 2025Article
- Insights into Virus-Host Interactions: Lessons from Caenorhabditis elegans-Orsay Virus Model.Current medical science · 2025Review
- Natural variation in infection specificity of Caenorhabditis briggsae isolates by two RNA viruses.PLoS pathogens · 2024Article
- Article
- CaeNDR, the Caenorhabditis Natural Diversity Resource.Nucleic acids research · 2024Article
- A Comparative Study of Life History Traits inmicroPublication biology · 2024Article
- Opposing directions of stage-specific body shape change in a close relative of C. elegans.BMC zoology · 2022Article
- Article
- Formation and function of dauer ascarosides in the nematodes Caenorhabditis briggsae and Caenorhabditis elegans.G3 (Bethesda, Md.) · 2022Article
- Non-Mendelian assortment of homologous autosomes of different sizes in males is the ancestral state in the Caenorhabditis lineage.Scientific reports · 2017Article
- A transcriptomic insight into the infective juvenile stage of the insect parasitic nematode, Heterorhabditis indica.BMC genomics · 2016Article
- Rapid creation of forward-genetics tools for C. briggsae using TALENs: lessons for nonmodel organisms.Molecular biology and evolution · 2014Article
- TGF-β signaling in C. elegans.WormBook : the online review of C. elegans biology · 2013Review
- A quantitative model of normal Caenorhabditis elegans embryogenesis and its disruption after stress.Developmental biology · 2013Article
- Genetic control of vulval development in Caenorhabditis briggsae.G3 (Bethesda, Md.) · 2012Article
- Population dynamics and habitat sharing of natural populations of Caenorhabditis elegans and C. briggsae.BMC biology · 2012Article
- Divergent gene expression in the conserved dauer stage of the nematodes Pristionchus pacificus and Caenorhabditis elegans.BMC genomics · 2012Article
- Host-finding behaviour in the nematode Pristionchus pacificus.Proceedings. Biological sciences · 2011Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular changes that underlie evolutionary changes in behavior and physiology are not well understood. Dauer formation in Caenorhabditis elegans is a temperature-sensitive process controlled through a network of signaling pathways associated with sensory neurons and is potentially an excellent system in which to investigate molecular changes in neuronal function during evolution. To begin to investigate the evolution of dauer formation in the genus Caenorhabditis at the molecular level, we isolated dauer-formation mutations in C. briggsae, a species closely related to the model organism C. elegans. We identified mutations in orthologs of C. elegans genes daf-2 (insulin receptor), daf-3 (Smad), and daf-4 (TGF-beta type 2 receptor), as well as genes required for formation of sensory cilia. Phenotypic analyses revealed that functions of these genes are conserved between C. elegans and C. briggsae. Analysis of C. briggsae mutations also revealed a significant difference between the two species in their responses to high temperatures (>26 degrees). C. elegans is strongly induced to form dauers at temperatures above 26 degrees, near the upper limit for growth of C. elegans. In contrast, C. briggsae, which is capable of growth at higher temperatures than C. elegans, lacks this response.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.