Trial reportBMC public health2007
The protocols for the 10/66 dementia research group population-based research programme.
Trial report in BMC public health, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 173 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
173 citing papers in PubMed, 7 syntheses or guidelines pooled it, 356 citations in OpenAlex.
- Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease.Genome biology · 2025Pooled it
- In Caring for Older People in Low- and Middle-Income Countries, Do Older Caregivers Have a High Level of Care Burden and Psychological Morbidity Compared to Younger Caregivers?International journal of environmental research and public health · 2022Pooled it
- Investigation of antihypertensive class, dementia, and cognitive decline: A meta-analysis.Neurology · 2020Pooled it
- Barriers and Facilitators of Engaging Community Health Workers in Non-Communicable Disease (NCD) Prevention and Control in China: A Systematic Review (2006⁻2016).International journal of environmental research and public health · 2018Pooled it
- Pooled it
- Dementia severity and weight loss: a comparison across eight cohorts. The 10/66 study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2013Pooled it
- Geographical variation in dementia: systematic review with meta-analysis.International journal of epidemiology · 2012Pooled it
- Advancing dementia preparedness in Low and Middle Income countries: A randomized trial to improve diagnosis in primary care.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Trial
- Late Life Learning, Cognition, and Aging: A Longitudinal study of middle and older-aged adults in Beirut, Lebanon (3LC study).medRxiv : the preprint server for health sciences · 2026Article
- Cohort Profile Update: cognition and ageing in the Survey of Health, Ageing and Retirement in Europe Harmonized Cognitive Assessment Protocol (SHARE-HCAP).International journal of epidemiology · 2026Article
- Normative cognitive data and psychometric validation of the 10/66 harmonized assessment protocol in Latin American.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Cohort profile: the Lebanon Study on Aging and HeAlth (LSAHA).BMC public health · 2025Article
- Cohort Profile: The Lebanon Study on Aging and HeAlth (LSAHA).Research square · 2025Article
- The Caribbean American Dementia and Aging Study: protocol for a population-based study of older adult health and dementia in Cuba, the Dominican Republic, and Puerto Rico.BMC geriatrics · 2025Article
- Cognitive impairment and dementia in Latin American individuals with parkinsonism and Parkinson's disease: A 10/66 Dementia Research Group study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Prevalence of Dementia in European, Chinese and Indian/Fijian-Indian Populations in Aotearoa New Zealand: A Protocol.International journal of geriatric psychiatry · 2025Article
- Beyond sleep: Rest and activity rhythm as a marker of preclinical and mild dementia in older adults with less education.Neurobiology of sleep and circadian rhythms · 2025Article
- APOE and Alzheimer's disease and related dementias risk among 12,221 Hispanics/Latinos.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Design and methodology of the harmonized diagnostic assessment of dementia for the longitudinal aging study in India: Wave 2.Journal of the American Geriatrics Society · 2025Article
- Validation of wellbeing scales among informal caregivers of Latinos with Alzheimer's disease and related dementias.Hispanic journal of behavioral sciences · 2025Article
113 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 13 institutions in 12 countries.
Funding
Abstract
backgroundLatin America, China and India are experiencing unprecedentedly rapid demographic ageing with an increasing number of people with dementia. The 10/66 Dementia Research Group's title refers to the 66% of people with dementia that live in developing countries and the less than one tenth of population-based research carried out in those settings. This paper describes the protocols for the 10/66 population-based and intervention studies that aim to redress this imbalance. METHODS/
designCross-sectional comprehensive one phase surveys have been conducted of all residents aged 65 and over of geographically defined catchment areas in ten low and middle income countries (India, China, Nigeria, Cuba, Dominican Republic, Brazil, Venezuela, Mexico, Peru and Argentina), with a sample size of between 1000 and 3000 (generally 2000). Each of the studies uses the same core minimum data set with cross-culturally validated assessments (dementia diagnosis and subtypes, mental disorders, physical health, anthropometry, demographics, extensive non communicable disease risk factor questionnaires, disability/functioning, health service utilisation, care arrangements and caregiver strain). Nested within the population based studies is a randomised controlled trial of a caregiver intervention for people with dementia and their families (ISRCTN41039907; ISRCTN41062011; ISRCTN95135433; ISRCTN66355402; ISRCTN93378627; ISRCTN94921815). A follow up of 2.5 to 3.5 years will be conducted in 7 countries (China, Cuba, Dominican Republic, Venezuela, Mexico, Peru and Argentina) to assess risk factors for incident dementia, stroke and all cause and cause-specific mortality; verbal autopsy will be used to identify causes of death. DISCUSSION: The 10/66 DRG baseline population-based studies are nearly complete. The incidence phase will be completed in 2009. All investigators are committed to establish an anonymised file sharing archive with monitored public access. Our aim is to create an evidence base to empower advocacy, raise awareness about dementia, and ensure that the health and social care needs of older people are anticipated and met.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.