ReviewCurrent opinion in chemical biology2007
High-throughput analysis of signals regulating stem cell fate and function.
Review in Current opinion in chemical biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 93 citations in OpenAlex.
- Evaluation of the efficacy of FDG-PET/CT in assessing the effects of BMMSC treatment in aged rhesus monkeys.Stem cell research & therapy · 2025Article
- Noninvasive andThe Analyst · 2025Article
- Current Advances in 3D Tissue and Organ Reconstruction.International journal of molecular sciences · 2021Review
- Current progress in hepatic tissue regeneration by tissue engineering.Journal of translational medicine · 2019Review
- High-throughput identification of factors promoting neuronal differentiation of human neural progenitor cells in microscale 3D cell culture.Biotechnology and bioengineering · 2019Article
- Modeling Physiological Events in 2D vs. 3D Cell Culture.Physiology (Bethesda, Md.) · 2017Review
- Leydig cell stem cells: Identification, proliferation and differentiation.Molecular and cellular endocrinology · 2017Review
- Application of biomaterials to advance induced pluripotent stem cell research and therapy.The EMBO journal · 2015Review
- Technology advancement for integrative stem cell analyses.Tissue engineering. Part B, Reviews · 2014Review
- Stem cells and modeling of autism spectrum disorders.Experimental neurology · 2014Review
- Biomaterial strategies for stem cell maintenance during in vitro expansion.Tissue engineering. Part B, Reviews · 2014Review
- A glimpse into the interactions of cells in a microenvironment: the modulation of T cells by mesenchymal stem cells.International journal of nanomedicine · 2014Article
- Platform for high-throughput testing of the effect of soluble compounds on 3D cell cultures.Analytical chemistry · 2013Article
- Control of cultured human cells with femtosecond laser ablated patterns on steel and plastic surfaces.Biomedical microdevices · 2013Article
- Deciphering the combinatorial roles of geometric, mechanical, and adhesion cues in regulation of cell spreading.PloS one · 2013Article
- Simplified microenvironments and reduced cell culture size influence the cell differentiation outcome in cellular microarrays.Journal of materials science. Materials in medicine · 2013Article
- Overview of micro- and nano-technology tools for stem cell applications: micropatterned and microelectronic devices.Sensors (Basel, Switzerland) · 2012Review
- Identification, proliferation, and differentiation of adult Leydig stem cells.Endocrinology · 2012Article
- Artificial niche microarrays for probing single stem cell fate in high throughput.Nature methods · 2011Article
- Stem cell biology and drug discovery.BMC biology · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Stem cells exhibit promise in numerous areas of regenerative medicine. Their fate and function are governed by a combination of intrinsic determinants and signals from the local microenvironment, or niche. An understanding of the mechanisms underlying both embryonic and adult stem cell functions has been greatly enhanced by the recent development of several high-throughput technologies: microfabricated platforms, including cellular microarrays, to investigate the combinatorial effects of microenvironmental stimuli and large-scale screens utilizing small molecules and short interfering RNAs to identify crucial genetic and signaling elements. Furthermore, the integration of these systems with other versatile platforms, such as microfluidics and lentiviral microarrays, will continue to enable the detailed elucidation of stem cell processes, and thus, greatly contribute to the development of stem cell based therapies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.