Evidence map›Paper›PMID 17653244›Full record

ArticleJournal of human hypertension2007

Association of novel promoter single nucleotide polymorphisms in vasopressin V1a receptor gene with essential hypertension in nonobese Japanese.

K N Hasan, M Shoji, K Sugimoto, S Tsutaya, E Matsuda, R Kudo, S Nakaji, T Suda, M Yasujima

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Journal of human hypertension, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. The AVPR1A Gene and Its Single Nucleotide Polymorphism rs10877969: A Literature Review of Associations with Health Conditions and Pain.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2018
    Review
  2. A common single nucleotide polymorphism alters the synthesis and secretion of neuropeptide Y.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

K N Hasan
M Shoji
K Sugimoto
S Tsutaya
E Matsuda
R Kudo
S Nakaji
T Suda
M Yasujima
Hirosaki University · JPHirosaki University Hospital · JPMeiji Pharmaceutical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the association between four novel single nucleotide polymorphisms (SNPs) in the promoter region of V1aR gene and essential hypertension in 620 Japanese subjects (365 hypertensives and 255 healthy). A significant association was found between one of the genotypes and alleles at SNP -6951 and hypertension in a subsample of nonobese individuals. This association demonstrated an independent risk for nonobese hypertension.

Indexed as

AllelesChi-Square DistributionFemaleGenotypeHumansHypertensionJapanLogistic ModelsMaleMiddle AgedPolymorphism, Single NucleotidePromoter Regions, GeneticReceptors, VasopressinReceptors, Vasopressin

Identifiers

PMID17653244
OpenAlexW1990553652

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.