ReviewInternational wound journal2007
Iodine revisited.
Review in International wound journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 121 citations in OpenAlex.
- Pooled it
- Proteomic study for the prediction ofHistochemistry and cell biology · 2026Article
- Plant Monoterpenes Geraniol, Eugenol and Carvacrol Against Multidrug-Resistant ESKAPE Isolates from Surgical Wounds.Antibiotics (Basel, Switzerland) · 2026Article
- Transport of Molecular Iodine From Antiseptic Iodophors across Hydrophilic-lipophilic Interfaces: Influence of Phospholipids.ACS omega · 2025Article
- Dilute Povidone-Iodine Irrigation: The Science of Molecular Iodine (I2) Kinetics and Its Antimicrobial Activity.The Journal of the American Academy of Orthopaedic Surgeons · 2025Review
- Antimicrobial hydrogel foam dressing with controlled release of gallium maltolate for infection control in chronic wounds.Bioactive materials · 2024Article
- Efficient and Selective, In Vitro and In Vivo, Antimicrobial Photodynamic Therapy with a Dicationic Chlorin in Combination with KI.ACS infectious diseases · 2024Article
- The effect of hyaluronic acid and iodine complex gel compared to Vaseline on deep second-degree burn wound in rats.International wound journal · 2024Article
- Antimicrobial Wound Dressings: A Concise Review for Clinicians.Antibiotics (Basel, Switzerland) · 2023Review
- Evaluation of the role of povidone‑iodine in the prevention of surgical site infections.Surgery open science · 2023Review
- Pediatric First-Degree Burn Management With Honey and 1% Silver Sulfadiazine (Ag-SD): Comparison and Contrast.Cureus · 2022Article
- The GenusMicroorganisms · 2022Review
- Molecular iodine is not responsible for cytotoxicity in iodophors.The Journal of hospital infection · 2022Article
- Topical Management of Wound: A Narrative Review of Cadexomer Iodine Ointment Versus Povidone Iodine Ointment.Cureus · 2022Review
- Topical Antibiofilm Agents With Potential Utility in the Treatment of Chronic Rhinosinusitis: A Narrative Review.Frontiers in pharmacology · 2022Review
- Adenotonsillectomy in high risk patients: Hematologic abnormalities and COVID-19 considerations.World journal of otorhinolaryngology - head and neck surgery · 2021Review
- Update on the role of antiseptics in the management of chronic wounds with critical colonisation and/or biofilm.International wound journal · 2021Review
- Antimicrobial stewardship of antiseptics that are pertinent to wounds: the need for a united approach.JAC-antimicrobial resistance · 2021Review
- Efficacy of a povidone-iodine foam dressing (Betafoam) on diabetic foot ulcer.International wound journal · 2020Article
- Polymeric Iodophors: Preparation, Properties, and Biomedical Applications.Review journal of chemistry · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iodine is an antiseptic that has been used in wound care for more than 150 years. Traditional formulations of iodine had serious limitations that were reduced in later products. Much has been written about iodine and opinions on its clinical efficacy are divided. There have been reviews of the chemical properties of iodine, its antimicrobial activity, human physiology, cytotoxicity and its clinical effectiveness, but few have addressed all these aspects. With the recent development of iodine-containing wound care products and the continued publication of laboratory and clinical studies, it seems timely to reassess the evidence relating to the effectiveness of iodine for treating wounds. This literature review attempts to provide an appropriate chemical and physiological background of the characteristics of iodine in order to provide a sound basis for understanding the available microbiological and clinical data. It will show that understanding the factors that contribute to the activity and potential cytotoxicity of iodine are important in evaluating the clinical evidence. Although definitive studies are needed, the sustained delivery of low doses of free iodine offers the potential to inhibit a broad range of microbial species without selecting for resistant strains or inducing cytotoxic effects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.