Evidence map›Paper›PMID 17645726›Full record

ArticleHuman cell2007

Establishment of a new cell line of endometrioid carcinoma of the ovary and its chemosensitivity.

Tomokazu Umezu, Hiroaki Kajiyama, Mikio Terauchi, Kiyosumi Shibata, Kazuhiko Ino, Akihiro Nawa, Fumitaka Kikkawa

Abstract read
PubMed Publisher
In one paragraph

Article in Human cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tomokazu UmezuDepartment of Obstetrics and Gynecology, Nagoya University, Graduate School of Medicine, Nagoya, Japan.
Hiroaki Kajiyama
Mikio Terauchi
Kiyosumi Shibata
Kazuhiko Ino
Akihiro Nawa
Fumitaka Kikkawa
Nagoya University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new cell line (NOE) of human ovarian endometrioid carcinoma was established and characterized. The cell line showed a short spindle-shaped morphology and continued to grow for more than 4 months without contact inhibition. The doubling time was approximately 15.5 h at the 10th passage. The chromosome number was aneuploid. The IC50 values of paclitaxel, cisplatin and carboplatin were 26.4 ng/mL, 2.4 microg/mL and 32.5 microg/mL, respectively. The NOE cells expressed estrogen receptor alpha. In nude mice, we confirmed tumor formation of NOE cells. These results indicated that NOE cells showed similar chemosensitivity and properties to those of the original tumor and might be useful in basic studies on the diagnosis, treatment and etiology of ovarian tumors.

Indexed as

AnimalsAntineoplastic AgentsCA-125 AntigenCarboplatinCarcinoma, EndometrioidCell DivisionCell Line, TumorChromosomes, HumanCisplatinEnzyme-Linked Immunosorbent AssayFemaleHumansMiceMice, Inbred BALB CMiddle AgedNeoplasm TransplantationAntineoplastic AgentsCA-125 AntigenCarboplatinCisplatinPaclitaxel

Identifiers

PMID17645726
OpenAlexW1966614713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.