ArticleJournal of bacteriology2007
Characterization and comparison of biofilm development by pathogenic and commensal isolates of Histophilus somni.
Article in Journal of bacteriology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 51 citations in OpenAlex.
- Article
- Contribution of Hfq to gene regulation and virulence inInfection and immunity · 2024Article
- Role of biofilms in antimicrobial resistance of the bacterial bovine respiratory disease complex.Frontiers in veterinary science · 2024Review
- The Role ofInfection and immunity · 2021Article
- Understanding How Staphylococcal Autolysin Domains Interact With Polystyrene Surfaces.Frontiers in microbiology · 2021Article
- Polymicrobial Biofilm Interaction BetweenFrontiers in microbiology · 2020Article
- Subinhibitory Concentrations of Amoxicillin, Lincomycin, and Oxytetracycline Commonly Used to Treat Swine IncreaseFrontiers in microbiology · 2018Article
- Article
- Closed Genome Sequences of SevenGenome announcements · 2017Article
- Antimicrobial Susceptibility of Bacteria That Cause Bovine Respiratory Disease Complex in Alberta, Canada.Frontiers in veterinary science · 2017Article
- Evolving views on bovine respiratory disease: An appraisal of selected key pathogens - Part 1.Veterinary journal (London, England : 1997) · 2016Review
- Histophilus somni Stimulates Expression of Antiviral Proteins and Inhibits BRSV Replication in Bovine Respiratory Epithelial Cells.PloS one · 2016Article
- Histophilosis as a Natural Disease.Current topics in microbiology and immunology · 2016Review
- Antimicrobial susceptibility of Histophilus somni isolated from clinically affected cattle in Australia.Veterinary journal (London, England : 1997) · 2015Article
- Characterization of Biofilm Formation in [Pasteurella] pneumotropica and [Actinobacillus] muris Isolates of Mouse Origin.PloS one · 2015Article
- Detection of antibodies to the biofilm exopolysaccharide of Histophilus somni following infection in cattle by enzyme-linked immunosorbent assay.Clinical and vaccine immunology : CVI · 2014Article
- Phenotypic switching in biofilm-forming marine bacterium Paenibacillus lautus NE3B01.Current microbiology · 2014Article
- Effect of Bacteriocins and Conditions that Mimic Food and Digestive Tract on Biofilm Formation, In Vitro Invasion of Eukaryotic Cells and Internalin Gene Expression by Listeria monocytogenes.Probiotics and antimicrobial proteins · 2013Article
- Diversity of bacterial species in the nasal cavity of sheep in the highlands of Ethiopia and first report of Histophilus somni in the country.Tropical animal health and production · 2013Article
- Prevention and treatment of virulent bacterial biofilms with an enzymatic nitric oxide-releasing dressing.Antimicrobial agents and chemotherapy · 2012Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Histophilus somni (Haemophilus somnus) is an obligate inhabitant of the mucosal surfaces of bovines and sheep and an opportunistic pathogen responsible for respiratory disease, meningoencephalitis, myocarditis, arthritis, and other systemic infections. The identification of an exopolysaccharide produced by H. somni prompted us to evaluate whether the bacterium was capable of forming a biofilm. After growth in polyvinyl chloride wells a biofilm was formed by all strains examined, although most isolates from systemic sites produced more biofilm than commensal isolates from the prepuce. Biofilms of pneumonia isolate strain 2336 and commensal isolate strain 129Pt were grown in flow cells, followed by analysis by confocal laser scanning microscopy and scanning electron microscopy. Both strains formed biofilms that went through stages of attachment, growth, maturation, and detachment. However, strain 2336 produced a mature biofilm that consisted of thick, homogenous mound-shaped microcolonies encased in an amorphous extracellular matrix with profound water channels. In contrast, strain 129Pt formed a biofilm of cell clusters that were tower-shaped or distinct filamentous structures intertwined with each other by strands of extracellular matrix. The biofilm of strain 2336 had a mass and thickness that was 5- to 10-fold greater than that of strain 129Pt and covered 75 to 82% of the surface area, whereas the biofilm of strain 129Pt covered 35 to 40% of the surface area. Since H. somni is an obligate inhabitant of the bovine and ovine host, the formation of a biofilm may be crucial to its persistence in vivo, and our in vitro evidence suggests that formation of a more robust biofilm may provide a selective advantage for strains that cause systemic disease.
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Registered trials
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