Evidence map›Paper›PMID 17643761›Full record

ArticleThe Journal of pediatrics2007

Five-year neurodevelopmental outcome of neonatal dehydration.

Gabriel J Escobar, Petra Liljestrand, Esther S Hudes, Donna M Ferriero, Yvonne W Wu, Rita J Jeremy, Thomas B Newman

Open access · greenAbstract read
In one paragraph

Article in The Journal of pediatrics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gabriel J EscobarDivision of Research, Perinatal Research Unit, Kaiser Permanente Medical Care Program, Oakland, CA 94612, USA. gabriel.escobar@kp.org
Petra Liljestrand
Esther S Hudes
Donna M Ferriero
Yvonne W Wu
Rita J Jeremy
Thomas B Newman
University of California, San Francisco · USKaiser Permanente Walnut Creek Medical Center · US

Funding

ZIDOVUDINE &LAMIVUDINE &NEVIRAPINE COMBINATION THERAPY IN HIV 1 INFM01RR001271 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KESSLER, DAVID A · 1985 to 2006
$22.7M
FIVE YEAR OUTCOME OF SEVERE NEONATAL JAUNDICE AND DEHYDRR01NS039683 · NINDS · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI NEWMAN, THOMAS B · 1999 to 2003
$1.7M
NCRR NIH HHS M01 RR001271NCRR NIH HHS M01 RR01271NINDS NIH HHS R01 NS039683NINDS NIH HHS R01 NS39683
6 · The paper itself

Abstract

objectiveTo determine the long-term outcome of neonatal dehydration. STUDY

designWe identified 182 newborns who were rehospitalized with dehydration (weight loss > or =12% of birth weight and/or serum sodium > or =150 mEq/L) and 419 randomly selected controls from a cohort of 106,627 term and near-term infants with birth weight > or =2000 g born between 1995 and 1998 in northern California Kaiser Permanente hospitals. Outcomes data were obtained from electronic records, interviews, questionnaire responses, and neurodevelopmental evaluations performed in a masked fashion.

resultsFollow-up data to age at least 2 years were available for 173 of 182 children with a history of dehydration (95%) and 372 of 419 controls (89%) and included formal evaluation at a mean age (+/-standard deviation) of 5.1 +/- 0.12 years for 106 children (58%) and 168 children (40%), respectively. None of the cases developed shock, gangrene, or respiratory failure. Neither crude nor adjusted scores on cognitive tests differed significantly between groups. There was no significant difference between groups in the proportion of children with abnormal neurologic examinations or neurologic diagnoses. Frequencies of parental concerns and reported behavior problems also were not significantly different in the 2 groups.

conclusionsNeonatal dehydration in this managed care setting was not associated with adverse neurodevelopmental outcomes in infants born at or near term.

Indexed as

Birth WeightCase-Control StudiesChild, PreschoolCohort StudiesDehydrationDevelopmental DisabilitiesFemaleFollow-Up StudiesHumansIncidenceInfantInfant, NewbornLearning DisabilitiesMaleMental DisordersMultivariate Analysis

Identifiers

PMID17643761
PMCPMC2233705
OpenAlexW2027709946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.