ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2007
Dietary protein intake and bone mineral content in adolescents-The Copenhagen Cohort Study.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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12 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Dietary protein and bone health across the life-course: an updated systematic review and meta-analysis over 40 years.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Pooled it
- Article
- Gastrointestinal In Vitro Digests of Infant Biscuits Formulated with Bovine Milk Proteins Positively Affect In Vitro Differentiation of Human Osteoblast-Like Cells.Foods (Basel, Switzerland) · 2020Article
- Nutrient intake of European adolescents: results of the HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) Study.Public health nutrition · 2014Article
- Milk consumption during teenage years and risk of hip fractures in older adults.JAMA pediatrics · 2014Article
- Protein intake from 0 to 18 years of age and its relation to health: a systematic literature review for the 5th Nordic Nutrition Recommendations.Food & nutrition research · 2013Article
- Protein intake, calcium balance and health consequences.European journal of clinical nutrition · 2012Review
- Determinants of bone mineral content and bone area in Indian preschool children.Journal of bone and mineral metabolism · 2011Article
- The interaction between dietary protein and bone health.Journal of bone and mineral metabolism · 2011Review
- Tracking of size-adjusted bone mineral content and bone area in boys and girls from 10 to 17 years of age.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2010Article
- Milk, rather than other foods, is associated with vertebral bone mass and circulating IGF-1 in female adolescents.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2009Article
- Genome-Wide Association Analysis of Longitudinal Bone Mineral Content Data From the Iowa Bone Development Study.Journal of clinical densitometry : the official journal of the International Society for Clinical DensitometryArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledData indicate that various protein sources may exhibit a differential effect on bone metabolism. We investigated associations of milk and meat protein intake with bone mineral content (BMC) in adolescents. Milk, but not meat, protein intake was positively associated with size-adjusted BMC. Milk-derived protein may be beneficial for bone mineralization.
introductionMilk and meat protein intake has been reported to exhibit a differential effect on serum insulin-like growth factor-I (IGF-I). IGF-I plays a key role in bone metabolism. Therefore, we investigated associations of different protein sources with BMC and bone area (BA) in adolescents.
methodsThis was a cross-sectional study of 17-year-old girls (n = 63) and boys (n = 46) participating in the second follow-up of The Copenhagen Cohort Study. We measured dietary intake (7-day food record), BMC and BA (dual-energy X-ray absorptiometry), serum markers for bone turnover and serum IGF-I (immunoassays).
resultsThe mean total protein intake ( approximately 1.2 g/kg) was modestly higher than that recommended. Total and milk ( approximately 0.3 g/kg) protein intake, but not meat protein intake ( approximately 0.4 g/kg), was positively associated with size-adjusted BMC (P <or= 0.05). The positive association between milk protein intake and size-adjusted BMC remained significant after correction for energy, calcium, and physical activity (P <or= 0.01) and did not seem to be mediated via current serum IGF-I. None of the analyzed protein sources was significantly associated with size-adjusted BA.
conclusionsOur results suggest that some components of milk protein may promote bone mineralization. Further studies are needed to elucidate this phenomenon.
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