ArticleNature chemical biology2007
Systems chemical biology.
Article in Nature chemical biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed.
- Testing the predictive power of reverse screening to infer drug targets, with the help of machine learning.Communications chemistry · 2024Article
- Drug Repurposing in Non-Small Cell Lung Carcinoma: Old Solutions for New Problems.Current oncology (Toronto, Ont.) · 2023Review
- Overcoming Drug Resistance in Advanced Prostate Cancer by Drug Repurposing.Medical sciences (Basel, Switzerland) · 2022Review
- Review
- Drug repurposing for breast cancer therapy: Old weapon for new battle.Seminars in cancer biology · 2021Review
- Has Drug Repurposing Fulfilled its Promise in Acute Myeloid Leukaemia?Journal of clinical medicine · 2020Review
- Predicting The Effects of Chemical-Protein Interactions On Proteins Using Tensor Factorisation.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2020Article
- Predicting proteome allocation, overflow metabolism, and metal requirements in a model acetogen.PLoS computational biology · 2019Article
- Drug repurposing: progress, challenges and recommendations.Nature reviews. Drug discovery · 2019Review
- Systemic QSAR and phenotypic virtual screening: chasing butterflies in drug discovery.Drug discovery today · 2017Review
- Multiscale Modeling in the Clinic: Drug Design and Development.Annals of biomedical engineering · 2016Review
- Predicting drug target interactions using meta-path-based semantic network analysis.BMC bioinformatics · 2016Article
- PAGER: constructing PAGs and new PAG-PAG relationships for network biology.Bioinformatics (Oxford, England) · 2015Article
- Identification of New Molecular Entities (NMEs) as Potential Leads against Tuberculosis from Open Source Compound Repository.PloS one · 2015Article
- QSAR modeling: where have you been? Where are you going to?Journal of medicinal chemistry · 2014Article
- Identification of odorant-receptor interactions by global mapping of the human odorome.PloS one · 2014Article
- Integrative approaches for predicting in vivo effects of chemicals from their structural descriptors and the results of short-term biological assays.Current topics in medicinal chemistry · 2014Review
- Integrated text mining and chemoinformatics analysis associates diet to health benefit at molecular level.PLoS computational biology · 2014Article
- A systems chemical biology study of malate synthase and isocitrate lyase inhibition in Mycobacterium tuberculosis during active and NRP growth.Computational biology and chemistry · 2013Article
- Network-based approaches in drug discovery and early development.Clinical pharmacology and therapeutics · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The increasing availability of data related to genes, proteins and their modulation by small molecules has provided a vast amount of biological information leading to the emergence of systems biology and the broad use of simulation tools for data analysis. However, there is a critical need to develop cheminformatics tools that can integrate chemical knowledge with these biological databases and simulation approaches, with the goal of creating systems chemical biology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.